Basic Information
Gene ID 373928
Gene Name PPAR gamma; PPARG
Full Name Peroxisome proliferator-activated receptor
Organism Gallus gallus [9031]

Cross Reference
UniProt Q9I878 UniGene Gga.3858
PDB NULL OMIM NULL
KEGG gga:373928 UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING 9031.ENSGALP00000007962

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSGALP00000007962 Gene3D G3DSA:1.10.565.10 IPR008946 162 192 2.10e-75 Nuclear hormone receptor, ligand-binding
ENSGALP00000007962 Gene3D G3DSA:1.10.565.10 IPR008946 248 472 2.10e-75 Nuclear hormone receptor, ligand-binding
ENSGALP00000007962 Gene3D G3DSA:3.30.50.10 IPR013088 109 161 2.10e-24 Zinc finger, NHR/GATA-type
ENSGALP00000007962 Pfam PF00104 IPR000536 289 454 2.10e-30 Nuclear hormone receptor, ligand-binding, core
ENSGALP00000007962 Pfam PF00105 IPR001628 108 174 2.40e-27 Zinc finger, nuclear hormone receptor-type
ENSGALP00000007962 Pfam PF12577 IPR022590 1 78 1.20e-34 Peroxisome proliferator-activated receptor gamma, N-terminal
ENSGALP00000007962 PRINTS PR00047 IPR001628 109 125 4.80e-19 Zinc finger, nuclear hormone receptor-type
ENSGALP00000007962 PRINTS PR00047 IPR001628 125 140 4.80e-19 Zinc finger, nuclear hormone receptor-type
ENSGALP00000007962 PRINTS PR00047 IPR001628 157 165 4.80e-19 Zinc finger, nuclear hormone receptor-type
ENSGALP00000007962 PRINTS PR00047 IPR001628 165 173 4.80e-19 Zinc finger, nuclear hormone receptor-type
ENSGALP00000007962 PRINTS PR00398 IPR001723 169 179 3.70e-28 Steroid hormone receptor
ENSGALP00000007962 PRINTS PR00398 IPR001723 286 307 3.70e-28 Steroid hormone receptor
ENSGALP00000007962 PRINTS PR00398 IPR001723 307 323 3.70e-28 Steroid hormone receptor
ENSGALP00000007962 PRINTS PR00398 IPR001723 375 390 3.70e-28 Steroid hormone receptor
ENSGALP00000007962 PRINTS PR00398 IPR001723 432 449 3.70e-28 Steroid hormone receptor
ENSGALP00000007962 PRINTS PR01288 IPR003074 198 212 9.40e-64 Peroxisome proliferator-activated receptor
ENSGALP00000007962 PRINTS PR01288 IPR003074 212 231 9.40e-64 Peroxisome proliferator-activated receptor
ENSGALP00000007962 PRINTS PR01288 IPR003074 325 338 9.40e-64 Peroxisome proliferator-activated receptor
ENSGALP00000007962 PRINTS PR01288 IPR003074 342 357 9.40e-64 Peroxisome proliferator-activated receptor
ENSGALP00000007962 PRINTS PR01288 IPR003074 360 373 9.40e-64 Peroxisome proliferator-activated receptor
ENSGALP00000007962 PRINTS PR01288 IPR003074 422 439 9.40e-64 Peroxisome proliferator-activated receptor
ENSGALP00000007962 PRINTS PR01288 IPR003074 456 468 9.40e-64 Peroxisome proliferator-activated receptor
ENSGALP00000007962 PRINTS PR01291 IPR003077 12 26 3.10e-47 Peroxisome proliferator-activated receptor, gamma
ENSGALP00000007962 PRINTS PR01291 IPR003077 185 201 3.10e-47 Peroxisome proliferator-activated receptor, gamma
ENSGALP00000007962 PRINTS PR01291 IPR003077 30 43 3.10e-47 Peroxisome proliferator-activated receptor, gamma
ENSGALP00000007962 PRINTS PR01291 IPR003077 409 422 3.10e-47 Peroxisome proliferator-activated receptor, gamma
ENSGALP00000007962 PRINTS PR01291 IPR003077 55 72 3.10e-47 Peroxisome proliferator-activated receptor, gamma
ENSGALP00000007962 PRINTS PR01291 IPR003077 73 91 3.10e-47 Peroxisome proliferator-activated receptor, gamma
ENSGALP00000007962 ProSitePatterns PS00031 IPR001628 109 135 - Zinc finger, nuclear hormone receptor-type
ENSGALP00000007962 ProSiteProfiles PS51030 IPR001628 106 180 0.00e-00 Zinc finger, nuclear hormone receptor-type
ENSGALP00000007962 SMART SM00399 IPR001628 106 176 8.50e-37 Zinc finger, nuclear hormone receptor-type
ENSGALP00000007962 SMART SM00430 IPR000536 285 444 6.10e-29 Nuclear hormone receptor, ligand-binding, core
ENSGALP00000007962 SUPERFAMILY SSF48508 IPR008946 210 473 0.00e-00 Nuclear hormone receptor, ligand-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSGALP00000007962 PF12577 5.3e-35 PPARgamma_N PPAR gamma N-terminal region
ENSGALP00000007962 PF00104 9.7e-31 Hormone_recep Ligand-binding domain of nuclear hormone receptor
ENSGALP00000007962 PF00105 1.3e-27 zf-C4 Zinc finger, C4 type (two domains)

Gene Ontology Annotation
Protein Entry Name Space Description
ENSGALP00000007962 GO:0000122 biological_process negative regulation of transcription from RNA polymerase II promoter
ENSGALP00000007962 GO:0001890 biological_process placenta development
ENSGALP00000007962 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSGALP00000007962 GO:0006919 biological_process activation of cysteine-type endopeptidase activity involved in apoptotic process
ENSGALP00000007962 GO:0008217 biological_process regulation of blood pressure
ENSGALP00000007962 GO:0010871 biological_process negative regulation of receptor biosynthetic process
ENSGALP00000007962 GO:0010887 biological_process negative regulation of cholesterol storage
ENSGALP00000007962 GO:0010891 biological_process negative regulation of sequestering of triglyceride
ENSGALP00000007962 GO:0015909 biological_process long-chain fatty acid transport
ENSGALP00000007962 GO:0030224 biological_process monocyte differentiation
ENSGALP00000007962 GO:0030855 biological_process epithelial cell differentiation
ENSGALP00000007962 GO:0032526 biological_process response to retinoic acid
ENSGALP00000007962 GO:0032869 biological_process cellular response to insulin stimulus
ENSGALP00000007962 GO:0035357 biological_process peroxisome proliferator activated receptor signaling pathway
ENSGALP00000007962 GO:0042593 biological_process glucose homeostasis
ENSGALP00000007962 GO:0042953 biological_process lipoprotein transport
ENSGALP00000007962 GO:0045165 biological_process cell fate commitment
ENSGALP00000007962 GO:0045600 biological_process positive regulation of fat cell differentiation
ENSGALP00000007962 GO:0045713 biological_process low-density lipoprotein particle receptor biosynthetic process
ENSGALP00000007962 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSGALP00000007962 GO:0048469 biological_process cell maturation
ENSGALP00000007962 GO:0048662 biological_process negative regulation of smooth muscle cell proliferation
ENSGALP00000007962 GO:0050872 biological_process white fat cell differentiation
ENSGALP00000007962 GO:0050873 biological_process brown fat cell differentiation
ENSGALP00000007962 GO:0051091 biological_process positive regulation of sequence-specific DNA binding transcription factor activity
ENSGALP00000007962 GO:0055098 biological_process response to low-density lipoprotein particle
ENSGALP00000007962 GO:0060336 biological_process negative regulation of interferon-gamma-mediated signaling pathway
ENSGALP00000007962 GO:0071285 biological_process cellular response to lithium ion
ENSGALP00000007962 GO:0005634 cellular_component nucleus
ENSGALP00000007962 GO:0005829 cellular_component cytosol
ENSGALP00000007962 GO:0001012 molecular_function RNA polymerase II regulatory region DNA binding
ENSGALP00000007962 GO:0003677 molecular_function DNA binding
ENSGALP00000007962 GO:0003682 molecular_function chromatin binding
ENSGALP00000007962 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSGALP00000007962 GO:0003707 molecular_function steroid hormone receptor activity
ENSGALP00000007962 GO:0004879 molecular_function ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
ENSGALP00000007962 GO:0008144 molecular_function drug binding
ENSGALP00000007962 GO:0008270 molecular_function zinc ion binding
ENSGALP00000007962 GO:0019899 molecular_function enzyme binding
ENSGALP00000007962 GO:0030374 molecular_function ligand-dependent nuclear receptor transcription coactivator activity
ENSGALP00000007962 GO:0033613 molecular_function activating transcription factor binding
ENSGALP00000007962 GO:0043565 molecular_function sequence-specific DNA binding
ENSGALP00000007962 GO:0046965 molecular_function retinoid X receptor binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9305 Sarcophilus harrisii 100934154 9669 Mustela putorius furo 101688974
10116 Rattus norvegicus 25664 9796 Equus caballus 100051258
61853 Nomascus leucogenys 100581046 10029 Cricetulus griseus 100689245
8128 Oreochromis niloticus 100711231 132113 Bombus impatiens 100744917
7463 Apis florea 100870379 143995 Megachile rotundata 100876784
34638 Metaseiulus occidentalis 100899165 30611 Otolemur garnettii 100943160
9597 Pan paniscus 100974825 39432 Saimiri boliviensis 101028278
9685 Felis catus 101095161 9595 Gorilla gorilla 101134077
59463 Myotis lucifugus 102435787 10090 Mus musculus 19016
9823 Sus scrofa 397671 7227 Drosophila melanogaster 39999
7460 Apis mellifera 410309 9646 Ailuropoda melanoleuca ENSAMEG00000004774
9358 Choloepus hoffmanni ENSCHOG00000007152 9361 Dasypus novemcinctus ENSDNOG00000018641
9365 Erinaceus europaeus ENSEEUG00000006334 9371 Echinops telfairi ENSETEG00000001775
69293 Gasterosteus aculeatus ENSGACG00000001665 8049 Gadus morhua ENSGMOG00000001375
7897 Latimeria chalumnae ENSLACG00000009212 9315 Macropus eugenii ENSMEUG00000007824
30608 Microcebus murinus ENSMICG00000016663 9544 Macaca mulatta ENSMMUG00000007191
9978 Ochotona princeps ENSOPRG00000003439 8090 Oryzias latipes ENSORLG00000004432
9813 Procavia capensis ENSPCAG00000001034 9601 Pongo abelii ENSPPYG00000013648
13735 Pelodiscus sinensis ENSPSIG00000011100 42254 Sorex araneus ENSSARG00000009808
43179 Ictidomys tridecemlineatus ENSSTOG00000012778 37347 Tupaia belangeri ENSTBEG00000011278
59729 Taeniopygia guttata ENSTGUG00000004069 31033 Takifugu rubripes ENSTRUG00000015522
9478 Tarsius syrichta ENSTSYG00000006950 9739 Tursiops truncatus ENSTTRG00000016565
30538 Vicugna pacos ENSVPAG00000011059 8364 Xenopus tropicalis ENSXETG00000017422
8083 Xiphophorus maculatus ENSXMAG00000017330 28377 Anolis carolinensis ENSACAG00000013360
9615 Canis familiaris ENSCAFG00000004991 7955 Danio rerio ENSDARG00000031848
9785 Loxodonta africana ENSLAFG00000030870 132908 Pteropus vampyrus ENSPVAG00000009845
99883 Tetraodon nigroviridis ENSTNIG00000014805