Basic Information
Gene ID ENSEEUG00000006334
Gene Name ENSEEUG00000006334
Full Name ENSEEUG00000006334
Organism Erinaceus europaeus [9365]

Cross Reference
UniProt NULL UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSEEUP00000005759 Gene3D G3DSA:1.10.565.10 IPR008946 164 194 1.10e-48 Nuclear hormone receptor, ligand-binding
ENSEEUP00000005759 Gene3D G3DSA:1.10.565.10 IPR008946 250 394 1.10e-48 Nuclear hormone receptor, ligand-binding
ENSEEUP00000005759 Gene3D G3DSA:3.30.50.10 IPR013088 111 163 1.60e-24 Zinc finger, NHR/GATA-type
ENSEEUP00000005759 Pfam PF00104 IPR000536 293 394 2.50e-17 Nuclear hormone receptor, ligand-binding, core
ENSEEUP00000005759 Pfam PF00105 IPR001628 110 176 1.80e-27 Zinc finger, nuclear hormone receptor-type
ENSEEUP00000005759 Pfam PF12577 IPR022590 3 80 2.40e-31 Peroxisome proliferator-activated receptor gamma, N-terminal
ENSEEUP00000005759 PRINTS PR00047 IPR001628 111 127 2.60e-19 Zinc finger, nuclear hormone receptor-type
ENSEEUP00000005759 PRINTS PR00047 IPR001628 127 142 2.60e-19 Zinc finger, nuclear hormone receptor-type
ENSEEUP00000005759 PRINTS PR00047 IPR001628 159 167 2.60e-19 Zinc finger, nuclear hormone receptor-type
ENSEEUP00000005759 PRINTS PR00047 IPR001628 167 175 2.60e-19 Zinc finger, nuclear hormone receptor-type
ENSEEUP00000005759 PRINTS PR00398 IPR001723 171 181 6.10e-20 Steroid hormone receptor
ENSEEUP00000005759 PRINTS PR00398 IPR001723 288 309 6.10e-20 Steroid hormone receptor
ENSEEUP00000005759 PRINTS PR00398 IPR001723 309 325 6.10e-20 Steroid hormone receptor
ENSEEUP00000005759 PRINTS PR00398 IPR001723 377 392 6.10e-20 Steroid hormone receptor
ENSEEUP00000005759 PRINTS PR01288 IPR003074 200 214 4.40e-46 Peroxisome proliferator-activated receptor
ENSEEUP00000005759 PRINTS PR01288 IPR003074 214 233 4.40e-46 Peroxisome proliferator-activated receptor
ENSEEUP00000005759 PRINTS PR01288 IPR003074 327 340 4.40e-46 Peroxisome proliferator-activated receptor
ENSEEUP00000005759 PRINTS PR01288 IPR003074 344 359 4.40e-46 Peroxisome proliferator-activated receptor
ENSEEUP00000005759 PRINTS PR01288 IPR003074 362 375 4.40e-46 Peroxisome proliferator-activated receptor
ENSEEUP00000005759 PRINTS PR01291 IPR003077 14 28 7.60e-41 Peroxisome proliferator-activated receptor, gamma
ENSEEUP00000005759 PRINTS PR01291 IPR003077 187 203 7.60e-41 Peroxisome proliferator-activated receptor, gamma
ENSEEUP00000005759 PRINTS PR01291 IPR003077 32 45 7.60e-41 Peroxisome proliferator-activated receptor, gamma
ENSEEUP00000005759 PRINTS PR01291 IPR003077 57 74 7.60e-41 Peroxisome proliferator-activated receptor, gamma
ENSEEUP00000005759 PRINTS PR01291 IPR003077 75 93 7.60e-41 Peroxisome proliferator-activated receptor, gamma
ENSEEUP00000005759 ProSitePatterns PS00031 IPR001628 111 137 - Zinc finger, nuclear hormone receptor-type
ENSEEUP00000005759 ProSiteProfiles PS51030 IPR001628 108 182 0.00e-00 Zinc finger, nuclear hormone receptor-type
ENSEEUP00000005759 SMART SM00399 IPR001628 108 178 8.50e-37 Zinc finger, nuclear hormone receptor-type
ENSEEUP00000005759 SUPERFAMILY SSF48508 IPR008946 212 394 0.00e-00 Nuclear hormone receptor, ligand-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSEEUP00000005759 PF12577 8.7e-32 PPARgamma_N PPAR gamma N-terminal region
ENSEEUP00000005759 PF00105 1.1e-27 zf-C4 Zinc finger, C4 type (two domains)
ENSEEUP00000005759 PF00104 1.2e-17 Hormone_recep Ligand-binding domain of nuclear hormone receptor

Gene Ontology Annotation
Protein Entry Name Space Description
ENSEEUP00000005759 GO:0000122 biological_process negative regulation of transcription from RNA polymerase II promoter
ENSEEUP00000005759 GO:0001890 biological_process placenta development
ENSEEUP00000005759 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSEEUP00000005759 GO:0006919 biological_process activation of cysteine-type endopeptidase activity involved in apoptotic process
ENSEEUP00000005759 GO:0008217 biological_process regulation of blood pressure
ENSEEUP00000005759 GO:0010871 biological_process negative regulation of receptor biosynthetic process
ENSEEUP00000005759 GO:0010887 biological_process negative regulation of cholesterol storage
ENSEEUP00000005759 GO:0010891 biological_process negative regulation of sequestering of triglyceride
ENSEEUP00000005759 GO:0015909 biological_process long-chain fatty acid transport
ENSEEUP00000005759 GO:0030224 biological_process monocyte differentiation
ENSEEUP00000005759 GO:0030855 biological_process epithelial cell differentiation
ENSEEUP00000005759 GO:0032526 biological_process response to retinoic acid
ENSEEUP00000005759 GO:0032869 biological_process cellular response to insulin stimulus
ENSEEUP00000005759 GO:0035357 biological_process peroxisome proliferator activated receptor signaling pathway
ENSEEUP00000005759 GO:0042593 biological_process glucose homeostasis
ENSEEUP00000005759 GO:0042953 biological_process lipoprotein transport
ENSEEUP00000005759 GO:0045165 biological_process cell fate commitment
ENSEEUP00000005759 GO:0045600 biological_process positive regulation of fat cell differentiation
ENSEEUP00000005759 GO:0045713 biological_process low-density lipoprotein particle receptor biosynthetic process
ENSEEUP00000005759 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSEEUP00000005759 GO:0048469 biological_process cell maturation
ENSEEUP00000005759 GO:0048662 biological_process negative regulation of smooth muscle cell proliferation
ENSEEUP00000005759 GO:0050872 biological_process white fat cell differentiation
ENSEEUP00000005759 GO:0050873 biological_process brown fat cell differentiation
ENSEEUP00000005759 GO:0051091 biological_process positive regulation of sequence-specific DNA binding transcription factor activity
ENSEEUP00000005759 GO:0055098 biological_process response to low-density lipoprotein particle
ENSEEUP00000005759 GO:0060336 biological_process negative regulation of interferon-gamma-mediated signaling pathway
ENSEEUP00000005759 GO:0071285 biological_process cellular response to lithium ion
ENSEEUP00000005759 GO:0005634 cellular_component nucleus
ENSEEUP00000005759 GO:0005829 cellular_component cytosol
ENSEEUP00000005759 GO:0001012 molecular_function RNA polymerase II regulatory region DNA binding
ENSEEUP00000005759 GO:0003677 molecular_function DNA binding
ENSEEUP00000005759 GO:0003682 molecular_function chromatin binding
ENSEEUP00000005759 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSEEUP00000005759 GO:0003707 molecular_function steroid hormone receptor activity
ENSEEUP00000005759 GO:0004879 molecular_function ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
ENSEEUP00000005759 GO:0008144 molecular_function drug binding
ENSEEUP00000005759 GO:0008270 molecular_function zinc ion binding
ENSEEUP00000005759 GO:0019899 molecular_function enzyme binding
ENSEEUP00000005759 GO:0030374 molecular_function ligand-dependent nuclear receptor transcription coactivator activity
ENSEEUP00000005759 GO:0033613 molecular_function activating transcription factor binding
ENSEEUP00000005759 GO:0043565 molecular_function sequence-specific DNA binding
ENSEEUP00000005759 GO:0046965 molecular_function retinoid X receptor binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
10224 Saccoglossus kowalevskii 100329099 9483 Callithrix jacchus 100415661
9305 Sarcophilus harrisii 100934154 9669 Mustela putorius furo 101688974
10116 Rattus norvegicus 25664 9031 Gallus gallus 373928
7668 Strongylocentrotus purpuratus 576339 28377 Anolis carolinensis ENSACAG00000013360
9615 Canis familiaris ENSCAFG00000004991 7955 Danio rerio ENSDARG00000031848
9796 Equus caballus 100051258 61853 Nomascus leucogenys 100581046
30195 Bombus terrestris 100644185 10029 Cricetulus griseus 100689245
8128 Oreochromis niloticus 100711231 132113 Bombus impatiens 100744917
143995 Megachile rotundata 100876784 30611 Otolemur garnettii 100943160
9597 Pan paniscus 100974825 9555 Papio anubis 101012073
39432 Saimiri boliviensis 101028278 9685 Felis catus 101095161
9595 Gorilla gorilla 101134077 59463 Myotis lucifugus 102435787
10090 Mus musculus 19016 9823 Sus scrofa 397671
7460 Apis mellifera 410309 7719 Ciona intestinalis 778733
9646 Ailuropoda melanoleuca ENSAMEG00000004774 9358 Choloepus hoffmanni ENSCHOG00000007152
9361 Dasypus novemcinctus ENSDNOG00000018641 10020 Dipodomys ordii ENSDORG00000003547
9371 Echinops telfairi ENSETEG00000001775 69293 Gasterosteus aculeatus ENSGACG00000001665
8049 Gadus morhua ENSGMOG00000001375 7897 Latimeria chalumnae ENSLACG00000009212
9315 Macropus eugenii ENSMEUG00000007824 9103 Meleagris gallopavo ENSMGAG00000013838
30608 Microcebus murinus ENSMICG00000016663 9544 Macaca mulatta ENSMMUG00000007191
9258 Ornithorhynchus anatinus ENSOANG00000006277 9986 Oryctolagus cuniculus ENSOCUG00000009353
9978 Ochotona princeps ENSOPRG00000003439 8090 Oryzias latipes ENSORLG00000004432
9813 Procavia capensis ENSPCAG00000001034 9601 Pongo abelii ENSPPYG00000013648
13735 Pelodiscus sinensis ENSPSIG00000011100 42254 Sorex araneus ENSSARG00000009808
43179 Ictidomys tridecemlineatus ENSSTOG00000012778 37347 Tupaia belangeri ENSTBEG00000011278
59729 Taeniopygia guttata ENSTGUG00000004069 31033 Takifugu rubripes ENSTRUG00000015522
9478 Tarsius syrichta ENSTSYG00000006950 9739 Tursiops truncatus ENSTTRG00000016565
30538 Vicugna pacos ENSVPAG00000011059 8364 Xenopus tropicalis ENSXETG00000017422
8083 Xiphophorus maculatus ENSXMAG00000017330 9785 Loxodonta africana ENSLAFG00000030870
132908 Pteropus vampyrus ENSPVAG00000009845 99883 Tetraodon nigroviridis ENSTNIG00000014805