Basic Information
Gene ID 100396711
Gene Name EPAS1
Full Name Endothelial PAS domain-containing protein 1
Organism Callithrix jacchus [9483]

Cross Reference
UniProt F6ZHN9 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSCJAP00000001230 Pfam PF00989 IPR013767 93 163 4.80e-05 PAS fold
ENSCJAP00000001230 Pfam PF08778 IPR014887 828 867 3.30e-20 HIF-1 alpha, transactivation domain, C-terminal
ENSCJAP00000001230 Pfam PF11413 IPR021537 514 546 9.40e-18 Hypoxia-inducible factor, alpha subunit
ENSCJAP00000001230 PRINTS PR00785 IPR001067 101 120 9.10e-07 Nuclear translocator
ENSCJAP00000001230 PRINTS PR00785 IPR001067 243 260 9.10e-07 Nuclear translocator
ENSCJAP00000001230 PRINTS PR00785 IPR001067 49 69 9.10e-07 Nuclear translocator
ENSCJAP00000001230 ProSiteProfiles PS50112 IPR000014 249 300 0.00e-00 PAS domain
ENSCJAP00000001230 ProSiteProfiles PS50112 IPR000014 92 147 0.00e-00 PAS domain
ENSCJAP00000001230 ProSiteProfiles PS50888 IPR011598 14 67 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
ENSCJAP00000001230 SMART SM00086 IPR001610 304 347 2.20e-11 PAC motif
ENSCJAP00000001230 SMART SM00091 IPR000014 232 298 3.70e-10 PAS domain
ENSCJAP00000001230 SMART SM00091 IPR000014 86 152 1.50e-11 PAS domain
ENSCJAP00000001230 SMART SM00353 IPR011598 20 75 1.30e-11 Myc-type, basic helix-loop-helix (bHLH) domain
ENSCJAP00000001230 SUPERFAMILY SSF47459 IPR011598 11 72 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
ENSCJAP00000001230 SUPERFAMILY SSF55785 IPR000014 244 346 0.00e-00 PAS domain
ENSCJAP00000001230 SUPERFAMILY SSF55785 IPR000014 95 202 0.00e-00 PAS domain
ENSCJAP00000001230 TIGRFAM TIGR00229 IPR000014 252 328 4.70e-08 PAS domain
ENSCJAP00000001230 TIGRFAM TIGR00229 IPR000014 98 150 1.00e-05 PAS domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSCJAP00000001230 PF14598 2.2e-28 PAS_11 PAS domain
ENSCJAP00000001230 PF08447 4.4e-25 PAS_3 PAS fold
ENSCJAP00000001230 PF08778 1.6e-20 HIF-1a_CTAD HIF-1 alpha C terminal transactivation domain
ENSCJAP00000001230 PF11413 4.3e-18 HIF-1 Hypoxia-inducible factor-1
ENSCJAP00000001230 PF00989 1.4e-14 PAS PAS fold
ENSCJAP00000001230 PF13426 8.3e-11 PAS_9 PAS domain
ENSCJAP00000001230 PF08448 1.3e-07 PAS_4 PAS fold

Gene Ontology Annotation
Protein Entry Name Space Description
ENSCJAP00000001230 GO:0001666 biological_process response to hypoxia
ENSCJAP00000001230 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSCJAP00000001230 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSCJAP00000001230 GO:0071456 biological_process cellular response to hypoxia
ENSCJAP00000001230 GO:0005634 cellular_component nucleus
ENSCJAP00000001230 GO:0005737 cellular_component cytoplasm
ENSCJAP00000001230 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSCJAP00000001230 GO:0004871 molecular_function signal transducer activity
ENSCJAP00000001230 GO:0035035 molecular_function histone acetyltransferase binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9597 Pan paniscus 100975248 39432 Saimiri boliviensis 101052563
9669 Mustela putorius furo 101679355 7897 Latimeria chalumnae 102357464
13735 Pelodiscus sinensis 102453156 9606 Homo sapiens 2034
9913 Bos taurus ENSBTAG00000003711 9615 Canis familiaris ENSCAFG00000002627
9358 Choloepus hoffmanni ENSCHOG00000005351 10141 Cavia porcellus ENSCPOG00000014242
7955 Danio rerio ENSDARG00000057671 10020 Dipodomys ordii ENSDORG00000003635
9796 Equus caballus ENSECAG00000014594 9031 Gallus gallus ENSGALG00000010005
8049 Gadus morhua ENSGMOG00000016337 9785 Loxodonta africana ENSLAFG00000012361
9315 Macropus eugenii ENSMEUG00000004035 9103 Meleagris gallopavo ENSMGAG00000010293
30608 Microcebus murinus ENSMICG00000002949 59463 Myotis lucifugus ENSMLUG00000007093
9986 Oryctolagus cuniculus ENSOCUG00000014904 30611 Otolemur garnettii ENSOGAG00000008084
9978 Ochotona princeps ENSOPRG00000010205 9813 Procavia capensis ENSPCAG00000014714
7757 Petromyzon marinus ENSPMAG00000009272 132908 Pteropus vampyrus ENSPVAG00000011259
10116 Rattus norvegicus ENSRNOG00000021318 43179 Ictidomys tridecemlineatus ENSSTOG00000012628
37347 Tupaia belangeri ENSTBEG00000004645 59729 Taeniopygia guttata ENSTGUG00000003933
99883 Tetraodon nigroviridis ENSTNIG00000009866 31033 Takifugu rubripes ENSTRUG00000005627
9478 Tarsius syrichta ENSTSYG00000001312 9739 Tursiops truncatus ENSTTRG00000011883
8364 Xenopus tropicalis ENSXETG00000026167 8083 Xiphophorus maculatus ENSXMAG00000004970
9646 Ailuropoda melanoleuca ENSAMEG00000006020 9361 Dasypus novemcinctus ENSDNOG00000005938
9365 Erinaceus europaeus ENSEEUG00000012802 9685 Felis catus ENSFCAG00000013629
69293 Gasterosteus aculeatus ENSGACG00000011414 9544 Macaca mulatta ENSMMUG00000023326
13616 Monodelphis domestica ENSMODG00000000953 9823 Sus scrofa ENSSSCG00000008443