Basic Information
Gene ID ENSTNIG00000009866
Gene Name EPAS1
Full Name Uncharacterized protein
Organism Tetraodon nigroviridis [99883]

Cross Reference
UniProt H3C1R7 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSTNIP00000002184 Pfam PF00989 IPR013767 19 85 4.10e-06 PAS fold
ENSTNIP00000002184 Pfam PF08778 IPR014887 760 799 6.10e-21 HIF-1 alpha, transactivation domain, C-terminal
ENSTNIP00000002184 Pfam PF11413 IPR021537 458 490 1.80e-16 Hypoxia-inducible factor, alpha subunit
ENSTNIP00000002184 ProSiteProfiles PS50112 IPR000014 176 227 0.00e-00 PAS domain
ENSTNIP00000002184 ProSiteProfiles PS50112 IPR000014 19 81 0.00e-00 PAS domain
ENSTNIP00000002184 SMART SM00086 IPR001610 231 274 3.00e-11 PAC motif
ENSTNIP00000002184 SMART SM00091 IPR000014 13 79 1.80e-11 PAS domain
ENSTNIP00000002184 SMART SM00091 IPR000014 157 225 3.60e-10 PAS domain
ENSTNIP00000002184 SUPERFAMILY SSF55785 IPR000014 171 273 0.00e-00 PAS domain
ENSTNIP00000002184 SUPERFAMILY SSF55785 IPR000014 22 131 0.00e-00 PAS domain
ENSTNIP00000002184 TIGRFAM TIGR00229 IPR000014 179 258 1.20e-09 PAS domain
ENSTNIP00000002184 TIGRFAM TIGR00229 IPR000014 24 80 3.10e-06 PAS domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSTNIP00000002184 PF14598 8.1e-30 PAS_11 PAS domain
ENSTNIP00000002184 PF08447 7.9e-28 PAS_3 PAS fold
ENSTNIP00000002184 PF08778 3.2e-21 HIF-1a_CTAD HIF-1 alpha C terminal transactivation domain
ENSTNIP00000002184 PF11413 8.2e-17 HIF-1 Hypoxia-inducible factor-1
ENSTNIP00000002184 PF00989 2.9e-16 PAS PAS fold
ENSTNIP00000002184 PF13426 2e-15 PAS_9 PAS domain
ENSTNIP00000002184 PF08448 6e-10 PAS_4 PAS fold

Gene Ontology Annotation
Protein Entry Name Space Description
ENSTNIP00000002184 GO:0001666 biological_process response to hypoxia
ENSTNIP00000002184 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSTNIP00000002184 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSTNIP00000002184 GO:0071456 biological_process cellular response to hypoxia
ENSTNIP00000002184 GO:0005634 cellular_component nucleus
ENSTNIP00000002184 GO:0005737 cellular_component cytoplasm
ENSTNIP00000002184 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSTNIP00000002184 GO:0004871 molecular_function signal transducer activity
ENSTNIP00000002184 GO:0035035 molecular_function histone acetyltransferase binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9483 Callithrix jacchus 100396711 13735 Pelodiscus sinensis 102453156
9606 Homo sapiens 2034 9646 Ailuropoda melanoleuca ENSAMEG00000006020
9913 Bos taurus ENSBTAG00000003711 9361 Dasypus novemcinctus ENSDNOG00000005938
9796 Equus caballus ENSECAG00000014594 9685 Felis catus ENSFCAG00000013629
69293 Gasterosteus aculeatus ENSGACG00000011414 30608 Microcebus murinus ENSMICG00000002949
9544 Macaca mulatta ENSMMUG00000023326 13616 Monodelphis domestica ENSMODG00000000953
9986 Oryctolagus cuniculus ENSOCUG00000014904 9823 Sus scrofa ENSSSCG00000008443
10224 Saccoglossus kowalevskii 100329032 9597 Pan paniscus 100975248
39432 Saimiri boliviensis 101052563 9669 Mustela putorius furo 101679355
7897 Latimeria chalumnae 102357464 9615 Canis familiaris ENSCAFG00000002627
9358 Choloepus hoffmanni ENSCHOG00000005351 10141 Cavia porcellus ENSCPOG00000014242
7955 Danio rerio ENSDARG00000057671 9031 Gallus gallus ENSGALG00000010005
8049 Gadus morhua ENSGMOG00000016337 9785 Loxodonta africana ENSLAFG00000012361
9315 Macropus eugenii ENSMEUG00000004035 9103 Meleagris gallopavo ENSMGAG00000010293
59463 Myotis lucifugus ENSMLUG00000007093 30611 Otolemur garnettii ENSOGAG00000008084
9978 Ochotona princeps ENSOPRG00000010205 8090 Oryzias latipes ENSORLG00000003535
132908 Pteropus vampyrus ENSPVAG00000011259 10116 Rattus norvegicus ENSRNOG00000021318
43179 Ictidomys tridecemlineatus ENSSTOG00000012628 37347 Tupaia belangeri ENSTBEG00000011941
59729 Taeniopygia guttata ENSTGUG00000003933 31033 Takifugu rubripes ENSTRUG00000005627
9478 Tarsius syrichta ENSTSYG00000001081 9739 Tursiops truncatus ENSTTRG00000011883
8364 Xenopus tropicalis ENSXETG00000026167 8083 Xiphophorus maculatus ENSXMAG00000004970