Basic Information
Gene ID ENSMMUG00000023326
Gene Name EPAS1
Full Name Uncharacterized protein
Organism Macaca mulatta [9544]

Cross Reference
UniProt F7EH03 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSMMUP00000030706 Pfam PF08778 IPR014887 821 860 3.30e-20 HIF-1 alpha, transactivation domain, C-terminal
ENSMMUP00000030706 Pfam PF11413 IPR021537 507 539 9.30e-18 Hypoxia-inducible factor, alpha subunit
ENSMMUP00000030706 PRINTS PR00785 IPR001067 234 251 8.90e-07 Nuclear translocator
ENSMMUP00000030706 PRINTS PR00785 IPR001067 41 61 8.90e-07 Nuclear translocator
ENSMMUP00000030706 PRINTS PR00785 IPR001067 93 112 8.90e-07 Nuclear translocator
ENSMMUP00000030706 ProSiteProfiles PS50112 IPR000014 240 291 0.00e-00 PAS domain
ENSMMUP00000030706 ProSiteProfiles PS50112 IPR000014 84 139 0.00e-00 PAS domain
ENSMMUP00000030706 ProSiteProfiles PS50888 IPR011598 6 59 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
ENSMMUP00000030706 SMART SM00086 IPR001610 295 338 2.20e-11 PAC motif
ENSMMUP00000030706 SMART SM00091 IPR000014 223 289 3.70e-10 PAS domain
ENSMMUP00000030706 SMART SM00091 IPR000014 78 144 1.50e-11 PAS domain
ENSMMUP00000030706 SMART SM00353 IPR011598 12 67 1.30e-11 Myc-type, basic helix-loop-helix (bHLH) domain
ENSMMUP00000030706 SUPERFAMILY SSF47459 IPR011598 3 64 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
ENSMMUP00000030706 SUPERFAMILY SSF55785 IPR000014 235 337 0.00e-00 PAS domain
ENSMMUP00000030706 SUPERFAMILY SSF55785 IPR000014 87 140 0.00e-00 PAS domain
ENSMMUP00000030706 TIGRFAM TIGR00229 IPR000014 243 319 4.70e-08 PAS domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSMMUP00000030706 PF14598 1.8e-28 PAS_11 PAS domain
ENSMMUP00000030706 PF08447 6.3e-25 PAS_3 PAS fold
ENSMMUP00000030706 PF08778 1.6e-20 HIF-1a_CTAD HIF-1 alpha C terminal transactivation domain
ENSMMUP00000030706 PF11413 4.3e-18 HIF-1 Hypoxia-inducible factor-1
ENSMMUP00000030706 PF00989 9.3e-14 PAS PAS fold
ENSMMUP00000030706 PF13426 1e-10 PAS_9 PAS domain
ENSMMUP00000030706 PF08448 6.5e-08 PAS_4 PAS fold

Gene Ontology Annotation
Protein Entry Name Space Description
ENSMMUP00000030706 GO:0001666 biological_process response to hypoxia
ENSMMUP00000030706 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSMMUP00000030706 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSMMUP00000030706 GO:0071456 biological_process cellular response to hypoxia
ENSMMUP00000030706 GO:0005634 cellular_component nucleus
ENSMMUP00000030706 GO:0005737 cellular_component cytoplasm
ENSMMUP00000030706 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSMMUP00000030706 GO:0004871 molecular_function signal transducer activity
ENSMMUP00000030706 GO:0035035 molecular_function histone acetyltransferase binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9646 Ailuropoda melanoleuca ENSAMEG00000006020 9361 Dasypus novemcinctus ENSDNOG00000005938
9365 Erinaceus europaeus ENSEEUG00000012802 9685 Felis catus ENSFCAG00000013629
7029 Acyrthosiphon pisum 100167974 10224 Saccoglossus kowalevskii 100329032
9483 Callithrix jacchus 100396711 61853 Nomascus leucogenys 100582446
8128 Oreochromis niloticus 100703737 9597 Pan paniscus 100975248
9555 Papio anubis 100999094 39432 Saimiri boliviensis 101052563
9669 Mustela putorius furo 101679355 7897 Latimeria chalumnae 102357464
13735 Pelodiscus sinensis 102453156 9606 Homo sapiens 2034
10090 Mus musculus 53417 7668 Strongylocentrotus purpuratus 577801
7070 Tribolium castaneum 655772 9598 Pan troglodytes 746195
28377 Anolis carolinensis ENSACAG00000016205 9913 Bos taurus ENSBTAG00000003711
9615 Canis familiaris ENSCAFG00000002627 9358 Choloepus hoffmanni ENSCHOG00000005351
10141 Cavia porcellus ENSCPOG00000014242 51511 Ciona savignyi ENSCSAVG00000005768
7955 Danio rerio ENSDARG00000057671 10020 Dipodomys ordii ENSDORG00000003635
9796 Equus caballus ENSECAG00000014594 69293 Gasterosteus aculeatus ENSGACG00000011414
9031 Gallus gallus ENSGALG00000010005 9595 Gorilla gorilla ENSGGOG00000003957
8049 Gadus morhua ENSGMOG00000016337 9785 Loxodonta africana ENSLAFG00000012361
9315 Macropus eugenii ENSMEUG00000004035 9103 Meleagris gallopavo ENSMGAG00000010293
30608 Microcebus murinus ENSMICG00000002949 59463 Myotis lucifugus ENSMLUG00000007093
13616 Monodelphis domestica ENSMODG00000000953 9258 Ornithorhynchus anatinus ENSOANG00000015360
9986 Oryctolagus cuniculus ENSOCUG00000014904 30611 Otolemur garnettii ENSOGAG00000008084
9978 Ochotona princeps ENSOPRG00000010205 8090 Oryzias latipes ENSORLG00000002004
9813 Procavia capensis ENSPCAG00000014714 7757 Petromyzon marinus ENSPMAG00000009272
9601 Pongo abelii ENSPPYG00000005881 132908 Pteropus vampyrus ENSPVAG00000011259
10116 Rattus norvegicus ENSRNOG00000021318 42254 Sorex araneus ENSSARG00000011198
9305 Sarcophilus harrisii ENSSHAG00000004128 9823 Sus scrofa ENSSSCG00000008443
43179 Ictidomys tridecemlineatus ENSSTOG00000012628 37347 Tupaia belangeri ENSTBEG00000004645
59729 Taeniopygia guttata ENSTGUG00000003933 99883 Tetraodon nigroviridis ENSTNIG00000009866
31033 Takifugu rubripes ENSTRUG00000005627 9478 Tarsius syrichta ENSTSYG00000001312
9739 Tursiops truncatus ENSTTRG00000011883 30538 Vicugna pacos ENSVPAG00000002395
8364 Xenopus tropicalis ENSXETG00000026167 8083 Xiphophorus maculatus ENSXMAG00000004970