Basic Information | |||
Gene ID | 100987766 | ||
Gene Name | STAT3 | ||
Full Name | PREDICTED: signal transducer and activator of transcription 3isoform 3 [Pan paniscus]. | ||
Organism | Pan paniscus [9597] |
Cross Reference | |||
UniProt | NULL | UniGene | NULL |
PDB | NULL | OMIM | NULL |
KEGG | NULL | UCSC | NULL |
Protein Interactions | |
DIP | NULL |
IntAct | NULL |
MINT | NULL |
STRING | NULL |
Ensembl/RefSeq | Transcript ID | Protein ID | Gene ID |
REFSEQ | |||
REFSEQ | |||
REFSEQ |
InterPro Annotation | |||||||
Protein | Program | Term | IPRS | Start | End | Score | Description |
XP_003813926 | Gene3D | G3DSA:1.10.238.10 | IPR011992 | 561 | 682 | 4.50e-59 | EF-hand domain pair |
XP_003813926 | Gene3D | G3DSA:1.10.532.10 | IPR013799 | 95 | 214 | 1.30e-45 | STAT transcription factor, protein interaction |
XP_003813926 | Gene3D | G3DSA:1.20.1050.20 | IPR013800 | 233 | 415 | 1.70e-72 | STAT transcription factor, all-alpha |
XP_003813926 | Gene3D | G3DSA:2.60.40.630 | IPR012345 | 416 | 560 | 7.10e-66 | STAT transcription factor, DNA-binding, subdomain |
XP_003813926 | Gene3D | G3DSA:3.30.505.10 | IPR000980 | 683 | 811 | 6.60e-52 | SH2 domain |
XP_003813926 | PANTHER | PTHR11801 | IPR001217 | 96 | 863 | 0.00e-00 | Transcription factor STAT |
XP_003813926 | Pfam | PF00017 | IPR000980 | 678 | 768 | 4.40e-13 | SH2 domain |
XP_003813926 | Pfam | PF01017 | IPR013800 | 233 | 413 | 4.50e-59 | STAT transcription factor, all-alpha |
XP_003813926 | Pfam | PF02864 | IPR013801 | 415 | 668 | 3.60e-127 | STAT transcription factor, DNA-binding |
XP_003813926 | Pfam | PF02865 | IPR013799 | 96 | 215 | 9.50e-42 | STAT transcription factor, protein interaction |
XP_003813926 | ProSiteProfiles | PS50001 | IPR000980 | 674 | 764 | 0.00e-00 | SH2 domain |
XP_003813926 | SMART | SM00252 | IPR000980 | 676 | 757 | 1.50e-03 | SH2 domain |
XP_003813926 | SMART | SM00964 | IPR013799 | 96 | 216 | 1.80e-64 | STAT transcription factor, protein interaction |
XP_003813926 | SUPERFAMILY | SSF47655 | IPR015988 | 230 | 415 | 0.00e-00 | STAT transcription factor, coiled coil |
XP_003813926 | SUPERFAMILY | SSF48092 | IPR013799 | 95 | 214 | 0.00e-00 | STAT transcription factor, protein interaction |
XP_003813926 | SUPERFAMILY | SSF49417 | IPR008967 | 416 | 669 | 0.00e-00 | p53-like transcription factor, DNA-binding |
Pfam Annotation | ||||
Protein | Pfam ID | E.value | Name | Description |
XP_003813926 | PF01017 | 0 | STAT_alpha | STAT protein, all-alpha domain |
XP_003813926 | PF02864 | 0 | STAT_bind | STAT protein, DNA binding domain |
XP_003813926 | PF02865 | 9.4994e-42 | STAT_int | STAT protein, protein interaction domain |
XP_003813926 | PF00017 | 1.7e-13 | SH2 | SH2 domain |
Gene Ontology Annotation | |||
Protein | Entry | Name Space | Description |
XP_003813926 | GO:0001659 | biological_process | temperature homeostasis |
XP_003813926 | GO:0001754 | biological_process | eye photoreceptor cell differentiation |
XP_003813926 | GO:0006357 | biological_process | regulation of transcription from RNA polymerase II promoter |
XP_003813926 | GO:0019953 | biological_process | sexual reproduction |
XP_003813926 | GO:0042593 | biological_process | glucose homeostasis |
XP_003813926 | GO:0042755 | biological_process | eating behavior |
XP_003813926 | GO:0045893 | biological_process | positive regulation of transcription, DNA-templated |
XP_003813926 | GO:0060397 | biological_process | JAK-STAT cascade involved in growth hormone signaling pathway |
XP_003813926 | GO:0005634 | cellular_component | nucleus |
XP_003813926 | GO:0005737 | cellular_component | cytoplasm |
XP_003813926 | GO:0005886 | cellular_component | plasma membrane |
XP_003813926 | GO:0003677 | molecular_function | DNA binding |
XP_003813926 | GO:0003700 | molecular_function | sequence-specific DNA binding transcription factor activity |
XP_003813926 | GO:0004871 | molecular_function | signal transducer activity |
XP_003813926 | GO:0005509 | molecular_function | calcium ion binding |
XP_003813926 | GO:0019901 | molecular_function | protein kinase binding |
XP_003813926 | GO:0043565 | molecular_function | sequence-specific DNA binding |
XP_003813926 | GO:0046983 | molecular_function | protein dimerization activity |
Orthologs | |||||
TAXID | Organism | Gene ID | TAXID | Organism | Gene ID |
10029 | Cricetulus griseus | 100755865 | 9986 | Oryctolagus cuniculus | 100348778 |
9555 | Papio anubis | 100998929 | 39432 | Saimiri boliviensis | 101049662 |
31033 | Takifugu rubripes | 101070968 | 8083 | Xiphophorus maculatus | 102226045 |
9646 | Ailuropoda melanoleuca | ENSAMEG00000006266 | 9358 | Choloepus hoffmanni | ENSCHOG00000009349 |
10020 | Dipodomys ordii | ENSDORG00000000308 | 9796 | Equus caballus | ENSECAG00000016439 |
8049 | Gadus morhua | ENSGMOG00000014955 | 9103 | Meleagris gallopavo | ENSMGAG00000003545 |
30608 | Microcebus murinus | ENSMICG00000012015 | 9669 | Mustela putorius furo | ENSMPUG00000010509 |
9258 | Ornithorhynchus anatinus | ENSOANG00000031491 | 30611 | Otolemur garnettii | ENSOGAG00000001517 |
8128 | Oreochromis niloticus | ENSONIG00000001148 | 9813 | Procavia capensis | ENSPCAG00000010265 |
9601 | Pongo abelii | ENSPPYG00000008392 | 13735 | Pelodiscus sinensis | ENSPSIG00000015868 |
9305 | Sarcophilus harrisii | ENSSHAG00000014833 | 43179 | Ictidomys tridecemlineatus | ENSSTOG00000006741 |
9478 | Tarsius syrichta | ENSTSYG00000012448 | 9739 | Tursiops truncatus | ENSTTRG00000007163 |
9685 | Felis catus | 101095698 | 9615 | Canis familiaris | 490967 |
28377 | Anolis carolinensis | ENSACAG00000017940 | 9483 | Callithrix jacchus | ENSCJAG00000000409 |
10141 | Cavia porcellus | ENSCPOG00000007939 | 9361 | Dasypus novemcinctus | ENSDNOG00000001471 |
69293 | Gasterosteus aculeatus | ENSGACG00000008607 | 9595 | Gorilla gorilla | ENSGGOG00000017110 |
7897 | Latimeria chalumnae | ENSLACG00000012019 | 9785 | Loxodonta africana | ENSLAFG00000014062 |
9315 | Macropus eugenii | ENSMEUG00000006663 | 59463 | Myotis lucifugus | ENSMLUG00000017449 |
9544 | Macaca mulatta | ENSMMUG00000010707 | 13616 | Monodelphis domestica | ENSMODG00000028212 |
9978 | Ochotona princeps | ENSOPRG00000008362 | 8090 | Oryzias latipes | ENSORLG00000004061 |
132908 | Pteropus vampyrus | ENSPVAG00000003885 | 42254 | Sorex araneus | ENSSARG00000014231 |
59729 | Taeniopygia guttata | ENSTGUG00000002600 | 8364 | Xenopus tropicalis | ENSXETG00000007642 |