Basic Information
Gene ID ENSPPYG00000008392
Gene Name STAT3
Full Name Signal transducer and activator of transcription
Organism Pongo abelii [9601]

Cross Reference
UniProt H2NU06 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSPPYP00000009437 Gene3D G3DSA:1.10.238.10 IPR011992 469 590 3.80e-59 EF-hand domain pair
ENSPPYP00000009437 Gene3D G3DSA:1.10.532.10 IPR013799 1 120 1.10e-45 STAT transcription factor, protein interaction
ENSPPYP00000009437 Gene3D G3DSA:1.20.1050.20 IPR013800 139 324 1.40e-70 STAT transcription factor, all-alpha
ENSPPYP00000009437 Gene3D G3DSA:2.60.40.630 IPR012345 325 468 5.20e-52 STAT transcription factor, DNA-binding, subdomain
ENSPPYP00000009437 Gene3D G3DSA:3.30.505.10 IPR000980 591 720 9.90e-52 SH2 domain
ENSPPYP00000009437 PANTHER PTHR11801 IPR001217 2 772 0.00e-00 Transcription factor STAT
ENSPPYP00000009437 Pfam PF00017 IPR000980 586 676 3.70e-13 SH2 domain
ENSPPYP00000009437 Pfam PF01017 IPR013800 139 322 4.00e-58 STAT transcription factor, all-alpha
ENSPPYP00000009437 Pfam PF02864 IPR013801 324 576 4.90e-113 STAT transcription factor, DNA-binding
ENSPPYP00000009437 Pfam PF02865 IPR013799 2 121 9.20e-42 STAT transcription factor, protein interaction
ENSPPYP00000009437 ProSiteProfiles PS50001 IPR000980 582 672 0.00e-00 SH2 domain
ENSPPYP00000009437 SMART SM00252 IPR000980 584 665 1.50e-03 SH2 domain
ENSPPYP00000009437 SMART SM00964 IPR013799 2 122 1.80e-64 STAT transcription factor, protein interaction
ENSPPYP00000009437 SUPERFAMILY SSF47655 IPR015988 136 324 0.00e-00 STAT transcription factor, coiled coil
ENSPPYP00000009437 SUPERFAMILY SSF48092 IPR013799 1 120 0.00e-00 STAT transcription factor, protein interaction
ENSPPYP00000009437 SUPERFAMILY SSF49417 IPR008967 325 577 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSPPYP00000009437 PF01017 0 STAT_alpha STAT protein, all-alpha domain
ENSPPYP00000009437 PF02864 0 STAT_bind STAT protein, DNA binding domain
ENSPPYP00000009437 PF02865 9.19952e-42 STAT_int STAT protein, protein interaction domain
ENSPPYP00000009437 PF00017 1.4e-13 SH2 SH2 domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSPPYP00000009437 GO:0001659 biological_process temperature homeostasis
ENSPPYP00000009437 GO:0001754 biological_process eye photoreceptor cell differentiation
ENSPPYP00000009437 GO:0006357 biological_process regulation of transcription from RNA polymerase II promoter
ENSPPYP00000009437 GO:0019953 biological_process sexual reproduction
ENSPPYP00000009437 GO:0042593 biological_process glucose homeostasis
ENSPPYP00000009437 GO:0042755 biological_process eating behavior
ENSPPYP00000009437 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSPPYP00000009437 GO:0060397 biological_process JAK-STAT cascade involved in growth hormone signaling pathway
ENSPPYP00000009437 GO:0005634 cellular_component nucleus
ENSPPYP00000009437 GO:0005737 cellular_component cytoplasm
ENSPPYP00000009437 GO:0005886 cellular_component plasma membrane
ENSPPYP00000009437 GO:0003677 molecular_function DNA binding
ENSPPYP00000009437 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSPPYP00000009437 GO:0004871 molecular_function signal transducer activity
ENSPPYP00000009437 GO:0005509 molecular_function calcium ion binding
ENSPPYP00000009437 GO:0019901 molecular_function protein kinase binding
ENSPPYP00000009437 GO:0043565 molecular_function sequence-specific DNA binding
ENSPPYP00000009437 GO:0046983 molecular_function protein dimerization activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
10029 Cricetulus griseus 100755865 9597 Pan paniscus 100987766
9685 Felis catus 101095698 9615 Canis familiaris 490967
28377 Anolis carolinensis ENSACAG00000017940 9646 Ailuropoda melanoleuca ENSAMEG00000006266
9358 Choloepus hoffmanni ENSCHOG00000009349 9483 Callithrix jacchus ENSCJAG00000000409
10141 Cavia porcellus ENSCPOG00000007939 9361 Dasypus novemcinctus ENSDNOG00000001471
69293 Gasterosteus aculeatus ENSGACG00000008607 9595 Gorilla gorilla ENSGGOG00000017110
7897 Latimeria chalumnae ENSLACG00000012019 9785 Loxodonta africana ENSLAFG00000014062
9315 Macropus eugenii ENSMEUG00000006663 59463 Myotis lucifugus ENSMLUG00000017449
9544 Macaca mulatta ENSMMUG00000010707 13616 Monodelphis domestica ENSMODG00000028212
9978 Ochotona princeps ENSOPRG00000008362 8090 Oryzias latipes ENSORLG00000004061
9986 Oryctolagus cuniculus 100348778 9555 Papio anubis 100998929
39432 Saimiri boliviensis 101049662 31033 Takifugu rubripes 101070968
8083 Xiphophorus maculatus 102226045 10020 Dipodomys ordii ENSDORG00000000308
9796 Equus caballus ENSECAG00000016439 8049 Gadus morhua ENSGMOG00000014955
9103 Meleagris gallopavo ENSMGAG00000003545 30608 Microcebus murinus ENSMICG00000012015
9669 Mustela putorius furo ENSMPUG00000010509 9258 Ornithorhynchus anatinus ENSOANG00000031491
30611 Otolemur garnettii ENSOGAG00000001517 8128 Oreochromis niloticus ENSONIG00000001148
9813 Procavia capensis ENSPCAG00000010265 13735 Pelodiscus sinensis ENSPSIG00000015868
43179 Ictidomys tridecemlineatus ENSSTOG00000006741 9739 Tursiops truncatus ENSTTRG00000007163
132908 Pteropus vampyrus ENSPVAG00000003885 42254 Sorex araneus ENSSARG00000014231
9305 Sarcophilus harrisii ENSSHAG00000014833 59729 Taeniopygia guttata ENSTGUG00000002600
9478 Tarsius syrichta ENSTSYG00000012448 8364 Xenopus tropicalis ENSXETG00000007642