Basic Information
Gene ID ENSLAFG00000014062
Gene Name STAT3
Full Name Signal transducer and activator of transcription
Organism Loxodonta africana [9785]

Cross Reference
UniProt G3TCI8 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSLAFP00000025834 Gene3D G3DSA:1.10.238.10 IPR011992 468 589 3.80e-59 EF-hand domain pair
ENSLAFP00000025834 Gene3D G3DSA:1.10.532.10 IPR013799 1 120 1.10e-45 STAT transcription factor, protein interaction
ENSLAFP00000025834 Gene3D G3DSA:1.20.1050.20 IPR013800 139 321 1.40e-72 STAT transcription factor, all-alpha
ENSLAFP00000025834 Gene3D G3DSA:2.60.40.630 IPR012345 322 467 1.10e-63 STAT transcription factor, DNA-binding, subdomain
ENSLAFP00000025834 Gene3D G3DSA:3.30.505.10 IPR000980 590 720 9.60e-52 SH2 domain
ENSLAFP00000025834 PANTHER PTHR11801 IPR001217 2 772 0.00e-00 Transcription factor STAT
ENSLAFP00000025834 Pfam PF00017 IPR000980 585 675 2.40e-13 SH2 domain
ENSLAFP00000025834 Pfam PF01017 IPR013800 139 319 3.70e-59 STAT transcription factor, all-alpha
ENSLAFP00000025834 Pfam PF02864 IPR013801 321 575 3.20e-125 STAT transcription factor, DNA-binding
ENSLAFP00000025834 Pfam PF02865 IPR013799 2 121 8.50e-42 STAT transcription factor, protein interaction
ENSLAFP00000025834 ProSiteProfiles PS50001 IPR000980 581 671 0.00e-00 SH2 domain
ENSLAFP00000025834 SMART SM00252 IPR000980 583 664 1.00e-03 SH2 domain
ENSLAFP00000025834 SMART SM00964 IPR013799 2 122 1.80e-64 STAT transcription factor, protein interaction
ENSLAFP00000025834 SUPERFAMILY SSF47655 IPR015988 136 321 0.00e-00 STAT transcription factor, coiled coil
ENSLAFP00000025834 SUPERFAMILY SSF48092 IPR013799 1 120 0.00e-00 STAT transcription factor, protein interaction
ENSLAFP00000025834 SUPERFAMILY SSF49417 IPR008967 322 576 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSLAFP00000025834 PF01017 0 STAT_alpha STAT protein, all-alpha domain
ENSLAFP00000025834 PF02864 0 STAT_bind STAT protein, DNA binding domain
ENSLAFP00000025834 PF02865 8.50028e-42 STAT_int STAT protein, protein interaction domain
ENSLAFP00000025834 PF00017 9e-14 SH2 SH2 domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSLAFP00000025834 GO:0001659 biological_process temperature homeostasis
ENSLAFP00000025834 GO:0001754 biological_process eye photoreceptor cell differentiation
ENSLAFP00000025834 GO:0006357 biological_process regulation of transcription from RNA polymerase II promoter
ENSLAFP00000025834 GO:0019953 biological_process sexual reproduction
ENSLAFP00000025834 GO:0042593 biological_process glucose homeostasis
ENSLAFP00000025834 GO:0042755 biological_process eating behavior
ENSLAFP00000025834 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSLAFP00000025834 GO:0060397 biological_process JAK-STAT cascade involved in growth hormone signaling pathway
ENSLAFP00000025834 GO:0005634 cellular_component nucleus
ENSLAFP00000025834 GO:0005737 cellular_component cytoplasm
ENSLAFP00000025834 GO:0005886 cellular_component plasma membrane
ENSLAFP00000025834 GO:0003677 molecular_function DNA binding
ENSLAFP00000025834 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSLAFP00000025834 GO:0004871 molecular_function signal transducer activity
ENSLAFP00000025834 GO:0005509 molecular_function calcium ion binding
ENSLAFP00000025834 GO:0019901 molecular_function protein kinase binding
ENSLAFP00000025834 GO:0043565 molecular_function