Basic Information
Gene ID ENSSTOG00000006741
Gene Name STAT3
Full Name Signal transducer and activator of transcription
Organism Ictidomys tridecemlineatus [43179]

Cross Reference
UniProt I3M8H8 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSSTOP00000006050 Gene3D G3DSA:1.10.238.10 IPR011992 379 500 3.10e-59 EF-hand domain pair
ENSSTOP00000006050 Gene3D G3DSA:1.10.532.10 IPR013799 2 32 8.40e-05 STAT transcription factor, protein interaction
ENSSTOP00000006050 Gene3D G3DSA:1.20.1050.20 IPR013800 51 233 1.10e-72 STAT transcription factor, all-alpha
ENSSTOP00000006050 Gene3D G3DSA:2.60.40.630 IPR012345 234 378 4.90e-66 STAT transcription factor, DNA-binding, subdomain
ENSSTOP00000006050 Gene3D G3DSA:3.30.505.10 IPR000980 501 629 4.60e-52 SH2 domain
ENSSTOP00000006050 PANTHER PTHR11801 IPR001217 1 681 0.00e-00 Transcription factor STAT
ENSSTOP00000006050 Pfam PF00017 IPR000980 496 586 3.10e-13 SH2 domain
ENSSTOP00000006050 Pfam PF01017 IPR013800 51 231 3.00e-59 STAT transcription factor, all-alpha
ENSSTOP00000006050 Pfam PF02864 IPR013801 233 486 2.30e-127 STAT transcription factor, DNA-binding
ENSSTOP00000006050 ProSiteProfiles PS50001 IPR000980 492 582 0.00e-00 SH2 domain
ENSSTOP00000006050 SMART SM00252 IPR000980 494 575 1.50e-03 SH2 domain
ENSSTOP00000006050 SUPERFAMILY SSF47655 IPR015988 48 233 0.00e-00 STAT transcription factor, coiled coil
ENSSTOP00000006050 SUPERFAMILY SSF49417 IPR008967 234 487 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSSTOP00000006050 PF01017 0 STAT_alpha STAT protein, all-alpha domain
ENSSTOP00000006050 PF02864 0 STAT_bind STAT protein, DNA binding domain
ENSSTOP00000006050 PF00017 1.1e-13 SH2 SH2 domain
ENSSTOP00000006050 PF02865 0.00035 STAT_int STAT protein, protein interaction domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSSTOP00000006050 GO:0001659 biological_process temperature homeostasis
ENSSTOP00000006050 GO:0001754 biological_process eye photoreceptor cell differentiation
ENSSTOP00000006050 GO:0006357 biological_process regulation of transcription from RNA polymerase II promoter
ENSSTOP00000006050 GO:0019953 biological_process sexual reproduction
ENSSTOP00000006050 GO:0042593 biological_process glucose homeostasis
ENSSTOP00000006050 GO:0042755 biological_process eating behavior
ENSSTOP00000006050 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSSTOP00000006050 GO:0060397 biological_process JAK-STAT cascade involved in growth hormone signaling pathway
ENSSTOP00000006050 GO:0005634 cellular_component nucleus
ENSSTOP00000006050 GO:0005737 cellular_component cytoplasm
ENSSTOP00000006050 GO:0005886 cellular_component plasma membrane
ENSSTOP00000006050 GO:0003677 molecular_function DNA binding
ENSSTOP00000006050 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSSTOP00000006050 GO:0004871 molecular_function signal transducer activity
ENSSTOP00000006050 GO:0005509 molecular_function calcium ion binding
ENSSTOP00000006050 GO:0019901 molecular_function protein kinase binding
ENSSTOP00000006050 GO:0043565 molecular_function sequence-specific DNA binding
ENSSTOP00000006050 GO:0046983 molecular_function protein dimerization activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
10029 Cricetulus griseus 100755865 9597 Pan paniscus 100987766
39432 Saimiri boliviensis 101049662 9685 Felis catus 101095698
8083 Xiphophorus maculatus 102226045 9615 Canis familiaris 490967
28377 Anolis carolinensis ENSACAG00000017940 9646 Ailuropoda melanoleuca ENSAMEG00000006266
9358 Choloepus hoffmanni ENSCHOG00000009349 9483 Callithrix jacchus ENSCJAG00000000409
10141 Cavia porcellus ENSCPOG00000007939 9361 Dasypus novemcinctus ENSDNOG00000001471
9796 Equus caballus ENSECAG00000016439 69293 Gasterosteus aculeatus ENSGACG00000008607
9595 Gorilla gorilla ENSGGOG00000017110 8049 Gadus morhua ENSGMOG00000014955
7897 Latimeria chalumnae ENSLACG00000012019 9785 Loxodonta africana ENSLAFG00000014062
9315 Macropus eugenii ENSMEUG00000006663 59463 Myotis lucifugus ENSMLUG00000017449
9544 Macaca mulatta ENSMMUG00000010707 13616 Monodelphis domestica ENSMODG00000028212
9258 Ornithorhynchus anatinus ENSOANG00000031491 30611 Otolemur garnettii ENSOGAG00000001517
8128 Oreochromis niloticus ENSONIG00000001148 9978 Ochotona princeps ENSOPRG00000008362
8090 Oryzias latipes ENSORLG00000004061 9601 Pongo abelii ENSPPYG00000008392
132908 Pteropus vampyrus ENSPVAG00000003885 42254 Sorex araneus ENSSARG00000014231
9305 Sarcophilus harrisii ENSSHAG00000014833 9986 Oryctolagus cuniculus 100348778
9555 Papio anubis 100998929 31033 Takifugu rubripes 101070968
10020 Dipodomys ordii ENSDORG00000000308 9103 Meleagris gallopavo ENSMGAG00000003545
30608 Microcebus murinus ENSMICG00000012015 9669 Mustela putorius furo ENSMPUG00000010509
9813 Procavia capensis ENSPCAG00000010265 13735 Pelodiscus sinensis ENSPSIG00000015868
9739 Tursiops truncatus ENSTTRG00000007163 59729 Taeniopygia guttata ENSTGUG00000002600
9478 Tarsius syrichta ENSTSYG00000012448 8364 Xenopus tropicalis ENSXETG00000007642