Basic Information
Gene ID ENSMGAG00000003545
Gene Name STAT3
Full Name Signal transducer and activator of transcription
Organism Meleagris gallopavo [9103]

Cross Reference
UniProt G1MWW8 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSMGAP00000003284 Gene3D G3DSA:1.10.238.10 IPR011992 467 588 3.80e-59 EF-hand domain pair
ENSMGAP00000003284 Gene3D G3DSA:1.10.532.10 IPR013799 1 120 1.10e-45 STAT transcription factor, protein interaction
ENSMGAP00000003284 Gene3D G3DSA:1.20.1050.20 IPR013800 139 321 1.40e-71 STAT transcription factor, all-alpha
ENSMGAP00000003284 Gene3D G3DSA:2.60.40.630 IPR012345 322 466 6.00e-66 STAT transcription factor, DNA-binding, subdomain
ENSMGAP00000003284 Gene3D G3DSA:3.30.505.10 IPR000980 589 718 7.90e-52 SH2 domain
ENSMGAP00000003284 PANTHER PTHR11801 IPR001217 2 771 0.00e-00 Transcription factor STAT
ENSMGAP00000003284 Pfam PF00017 IPR000980 584 674 8.10e-13 SH2 domain
ENSMGAP00000003284 Pfam PF01017 IPR013800 139 319 3.00e-58 STAT transcription factor, all-alpha
ENSMGAP00000003284 Pfam PF02864 IPR013801 321 574 2.90e-127 STAT transcription factor, DNA-binding
ENSMGAP00000003284 Pfam PF02865 IPR013799 2 121 8.30e-42 STAT transcription factor, protein interaction
ENSMGAP00000003284 ProSiteProfiles PS50001 IPR000980 580 670 0.00e-00 SH2 domain
ENSMGAP00000003284 SMART SM00252 IPR000980 582 663 1.00e-03 SH2 domain
ENSMGAP00000003284 SMART SM00964 IPR013799 2 122 7.00e-65 STAT transcription factor, protein interaction
ENSMGAP00000003284 SUPERFAMILY SSF47655 IPR015988 136 321 0.00e-00 STAT transcription factor, coiled coil
ENSMGAP00000003284 SUPERFAMILY SSF48092 IPR013799 1 120 0.00e-00 STAT transcription factor, protein interaction
ENSMGAP00000003284 SUPERFAMILY SSF49417 IPR008967 322 575 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSMGAP00000003284 PF01017 0 STAT_alpha STAT protein, all-alpha domain
ENSMGAP00000003284 PF02864 0 STAT_bind STAT protein, DNA binding domain
ENSMGAP00000003284 PF02865 8.29989e-42 STAT_int STAT protein, protein interaction domain
ENSMGAP00000003284 PF00017 3e-13 SH2 SH2 domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSMGAP00000003284 GO:0001659 biological_process temperature homeostasis
ENSMGAP00000003284 GO:0001754 biological_process eye photoreceptor cell differentiation
ENSMGAP00000003284 GO:0006357 biological_process regulation of transcription from RNA polymerase II promoter
ENSMGAP00000003284 GO:0019953 biological_process sexual reproduction
ENSMGAP00000003284 GO:0042593 biological_process glucose homeostasis
ENSMGAP00000003284 GO:0042755 biological_process eating behavior
ENSMGAP00000003284 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSMGAP00000003284 GO:0060397 biological_process JAK-STAT cascade involved in growth hormone signaling pathway
ENSMGAP00000003284 GO:0005634 cellular_component nucleus
ENSMGAP00000003284 GO:0005737 cellular_component cytoplasm
ENSMGAP00000003284 GO:0005886 cellular_component plasma membrane
ENSMGAP00000003284 GO:0003677 molecular_function DNA binding
ENSMGAP00000003284 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSMGAP00000003284 GO:0004871 molecular_function signal transducer activity
ENSMGAP00000003284 GO:0005509 molecular_function calcium ion binding
ENSMGAP00000003284 GO:0019901 molecular_function protein kinase binding
ENSMGAP00000003284 GO:0043565 molecular_function sequence-specific DNA binding
ENSMGAP00000003284 GO:0046983 molecular_function protein dimerization activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
10029 Cricetulus griseus 100755865 9597 Pan paniscus 100987766
9555 Papio anubis 100998929 39432 Saimiri boliviensis 101049662
9685 Felis catus 101095698 8083 Xiphophorus maculatus 102226045
9615 Canis familiaris 490967 28377 Anolis carolinensis ENSACAG00000017940
9646 Ailuropoda melanoleuca ENSAMEG00000006266 9358 Choloepus hoffmanni ENSCHOG00000009349
9483 Callithrix jacchus ENSCJAG00000000409 10141 Cavia porcellus ENSCPOG00000007939
9361 Dasypus novemcinctus ENSDNOG00000001471 9796 Equus caballus ENSECAG00000016439
69293 Gasterosteus aculeatus ENSGACG00000008607 9595 Gorilla gorilla ENSGGOG00000017110
8049 Gadus morhua ENSGMOG00000014955 7897 Latimeria chalumnae ENSLACG00000012019
9785 Loxodonta africana ENSLAFG00000014062 9315 Macropus eugenii ENSMEUG00000006663
9986 Oryctolagus cuniculus 100348778 31033 Takifugu rubripes 101070968
10020 Dipodomys ordii ENSDORG00000000308 30608 Microcebus murinus ENSMICG00000012015
13735 Pelodiscus sinensis ENSPSIG00000015868 9739 Tursiops truncatus ENSTTRG00000007163
59463 Myotis lucifugus ENSMLUG00000017449 9544 Macaca mulatta ENSMMUG00000010707
13616 Monodelphis domestica ENSMODG00000028212 9669 Mustela putorius furo ENSMPUG00000010509
30611 Otolemur garnettii ENSOGAG00000001517 8128 Oreochromis niloticus ENSONIG00000001148
9978 Ochotona princeps ENSOPRG00000008362 8090 Oryzias latipes ENSORLG00000004061
9813 Procavia capensis ENSPCAG00000010265 9601 Pongo abelii ENSPPYG00000008392
132908 Pteropus vampyrus ENSPVAG00000003885 42254 Sorex araneus ENSSARG00000014231
9305 Sarcophilus harrisii ENSSHAG00000014833 43179 Ictidomys tridecemlineatus ENSSTOG00000006741
59729 Taeniopygia guttata ENSTGUG00000002600 9478 Tarsius syrichta ENSTSYG00000012448
8364 Xenopus tropicalis ENSXETG00000007642