Basic Information
Gene ID ENSAMEG00000001224
Gene Name EN2
Full Name Homeobox protein engrailed
Organism Ailuropoda melanoleuca [9646]

Cross Reference
UniProt G1L323 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSAMEP00000001283 Gene3D G3DSA:1.10.10.60 IPR009057 143 217 1.40e-25 Homeodomain-like
ENSAMEP00000001283 Pfam PF00046 IPR001356 160 216 7.00e-22 Homeobox domain
ENSAMEP00000001283 Pfam PF10525 IPR019549 217 248 1.30e-18 Homeobox engrailed, C-terminal
ENSAMEP00000001283 PRINTS PR00024 IPR020479 181 192 1.10e-06 Homeodomain, metazoa
ENSAMEP00000001283 PRINTS PR00024 IPR020479 196 206 1.10e-06 Homeodomain, metazoa
ENSAMEP00000001283 PRINTS PR00024 IPR020479 206 215 1.10e-06 Homeodomain, metazoa
ENSAMEP00000001283 PRINTS PR00026 IPR000747 158 175 4.60e-18 Homeodomain engrailed
ENSAMEP00000001283 PRINTS PR00026 IPR000747 221 238 4.60e-18 Homeodomain engrailed
ENSAMEP00000001283 ProSitePatterns PS00027 IPR017970 192 215 - Homeobox, conserved site
ENSAMEP00000001283 ProSitePatterns PS00033 IPR019737 228 235 - Homeobox engrailed-type, conserved site
ENSAMEP00000001283 ProSiteProfiles PS50071 IPR001356 157 217 0.00e-00 Homeobox domain
ENSAMEP00000001283 SMART SM00389 IPR001356 159 221 7.10e-28 Homeobox domain
ENSAMEP00000001283 SUPERFAMILY SSF46689 IPR009057 150 216 0.00e-00 Homeodomain-like

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSAMEP00000001283 PF00046 4.4e-22 Homeobox Homeobox domain
ENSAMEP00000001283 PF10525 6.7e-19 Engrail_1_C_sig Engrailed homeobox C-terminal signature domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSAMEP00000001283 GO:0005634 cellular_component nucleus
ENSAMEP00000001283 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7425 Nasonia vitripennis 100123902 10224 Saccoglossus kowalevskii 100303466
9601 Pongo abelii 100459532 9823 Sus scrofa 100512078
61853 Nomascus leucogenys 100581025 30195 Bombus terrestris 100649797
8128 Oreochromis niloticus 100706716 132113 Bombus impatiens 100743858
7463 Apis florea 100870890 143995 Megachile rotundata 100882481
34638 Metaseiulus occidentalis 100908620 30611 Otolemur garnettii 100946410
9597 Pan paniscus 100996220 9555 Papio anubis 101019723
39432 Saimiri boliviensis 101033660 31033 Takifugu rubripes 101068755
43179 Ictidomys tridecemlineatus 101960578 8083 Xiphophorus maculatus 102234767
7897 Latimeria chalumnae 102360063 7227 Drosophila melanogaster 36240
7719 Ciona intestinalis 445653 7668 Strongylocentrotus purpuratus 590038
7070 Tribolium castaneum 661645 9544 Macaca mulatta 716307
7460 Apis mellifera 725151 9606 Homo sapiens 2020
8364 Xenopus tropicalis ENSXETG00000014994 9913 Bos taurus ENSBTAG00000018917
9615 Canis familiaris ENSCAFG00000005082 9483 Callithrix jacchus ENSCJAG00000017450
10141 Cavia porcellus ENSCPOG00000024572 51511 Ciona savignyi ENSCSAVG00000008099
7955 Danio rerio ENSDARG00000038868 9796 Equus caballus ENSECAG00000021744
9365 Erinaceus europaeus ENSEEUG00000004213 9371 Echinops telfairi ENSETEG00000004995
9685 Felis catus ENSFCAG00000023560 69293 Gasterosteus aculeatus ENSGACG00000003888
9595 Gorilla gorilla ENSGGOG00000022981 8049 Gadus morhua ENSGMOG00000004983
9785 Loxodonta africana ENSLAFG00000032115 9103 Meleagris gallopavo ENSMGAG00000012331
59463 Myotis lucifugus ENSMLUG00000004165 13616 Monodelphis domestica ENSMODG00000004978
9669 Mustela putorius furo ENSMPUG00000009596 9258 Ornithorhynchus anatinus ENSOANG00000006149
9986 Oryctolagus cuniculus ENSOCUG00000002453 8090 Oryzias latipes ENSORLG00000010437
13735 Pelodiscus sinensis ENSPSIG00000014871 132908 Pteropus vampyrus ENSPVAG00000003106
59729 Taeniopygia guttata ENSTGUG00000000695 99883 Tetraodon nigroviridis ENSTNIG00000012777
9739 Tursiops truncatus ENSTTRG00000013702

Paralogs
ENSAMEG00000008454