Basic Information
Gene ID ENSOANG00000006149
Gene Name EN2
Full Name Homeobox protein engrailed
Organism Ornithorhynchus anatinus [9258]

Cross Reference
UniProt F7CFP3 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSOANP00000009822 Gene3D G3DSA:1.10.10.60 IPR009057 94 173 4.00e-28 Homeodomain-like
ENSOANP00000009822 Pfam PF00046 IPR001356 116 172 4.90e-22 Homeobox domain
ENSOANP00000009822 Pfam PF10525 IPR019549 173 204 5.50e-19 Homeobox engrailed, C-terminal
ENSOANP00000009822 PRINTS PR00024 IPR020479 137 148 7.10e-07 Homeodomain, metazoa
ENSOANP00000009822 PRINTS PR00024 IPR020479 152 162 7.10e-07 Homeodomain, metazoa
ENSOANP00000009822 PRINTS PR00024 IPR020479 162 171 7.10e-07 Homeodomain, metazoa
ENSOANP00000009822 PRINTS PR00026 IPR000747 114 131 3.40e-18 Homeodomain engrailed
ENSOANP00000009822 PRINTS PR00026 IPR000747 177 194 3.40e-18 Homeodomain engrailed
ENSOANP00000009822 ProSitePatterns PS00027 IPR017970 148 171 - Homeobox, conserved site
ENSOANP00000009822 ProSitePatterns PS00033 IPR019737 184 191 - Homeobox engrailed-type, conserved site
ENSOANP00000009822 ProSiteProfiles PS50071 IPR001356 113 173 0.00e-00 Homeobox domain
ENSOANP00000009822 SMART SM00389 IPR001356 115 177 7.10e-28 Homeobox domain
ENSOANP00000009822 SUPERFAMILY SSF46689 IPR009057 104 172 0.00e-00 Homeodomain-like

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSOANP00000009822 PF00046 3.6e-22 Homeobox Homeobox domain
ENSOANP00000009822 PF10525 2.6e-19 Engrail_1_C_sig Engrailed homeobox C-terminal signature domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSOANP00000009822 GO:0005634 cellular_component nucleus
ENSOANP00000009822 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSOANP00000009822 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7029 Acyrthosiphon pisum 100161671 10224 Saccoglossus kowalevskii 100303466
9823 Sus scrofa 100512078 61853 Nomascus leucogenys 100581025
30195 Bombus terrestris 100649797 8128 Oreochromis niloticus 100706716
132113 Bombus impatiens 100743858 7463 Apis florea 100870890
143995 Megachile rotundata 100882481 34638 Metaseiulus occidentalis 100908620
30611 Otolemur garnettii 100946410 9597 Pan paniscus 100996220
9555 Papio anubis 101019723 39432 Saimiri boliviensis 101033660
31033 Takifugu rubripes 101068755 8083 Xiphophorus maculatus 102234767
7897 Latimeria chalumnae 102360063 7227 Drosophila melanogaster 36240
7719 Ciona intestinalis 445653 7070 Tribolium castaneum 661645
9544 Macaca mulatta 716307 7460 Apis mellifera 725151
28377 Anolis carolinensis ENSACAG00000011018 9913 Bos taurus ENSBTAG00000018917
9615 Canis familiaris ENSCAFG00000005082 9483 Callithrix jacchus ENSCJAG00000017450
10141 Cavia porcellus ENSCPOG00000024572 51511 Ciona savignyi ENSCSAVG00000008099
7955 Danio rerio ENSDARG00000038868 9796 Equus caballus ENSECAG00000021744
9365 Erinaceus europaeus ENSEEUG00000004213 9371 Echinops telfairi ENSETEG00000004995
9685 Felis catus ENSFCAG00000023560 69293 Gasterosteus aculeatus ENSGACG00000003888
9595 Gorilla gorilla ENSGGOG00000022981 8049 Gadus morhua ENSGMOG00000004983
9785 Loxodonta africana ENSLAFG00000032115 9103 Meleagris gallopavo ENSMGAG00000012331
30608 Microcebus murinus ENSMICG00000017594 59463 Myotis lucifugus ENSMLUG00000004165
13616 Monodelphis domestica ENSMODG00000004978 9669 Mustela putorius furo ENSMPUG00000009596
7425 Nasonia vitripennis 100123905 9601 Pongo abelii 100459532
43179 Ictidomys tridecemlineatus 101960578 9606 Homo sapiens 2020
7668 Strongylocentrotus purpuratus 590038 9646 Ailuropoda melanoleuca ENSAMEG00000001224
99883 Tetraodon nigroviridis ENSTNIG00000012777 8364 Xenopus tropicalis ENSXETG00000014994
9986 Oryctolagus cuniculus ENSOCUG00000002453 9978 Ochotona princeps ENSOPRG00000015660
8090 Oryzias latipes ENSORLG00000010437 13735 Pelodiscus sinensis ENSPSIG00000014871
9598 Pan troglodytes ENSPTRG00000016137 132908 Pteropus vampyrus ENSPVAG00000003106
10116 Rattus norvegicus ENSRNOG00000046462 9305 Sarcophilus harrisii ENSSHAG00000017591
59729 Taeniopygia guttata ENSTGUG00000000695 9739 Tursiops truncatus ENSTTRG00000013702

Paralogs
ENSOANG00000002989