Basic Information
Gene ID ENSMODG00000004978
Gene Name EN2
Full Name Homeobox protein engrailed
Organism Monodelphis domestica [13616]

Cross Reference
UniProt F7FKY3 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSMODP00000006129 Gene3D G3DSA:1.10.10.60 IPR009057 230 304 2.60e-25 Homeodomain-like
ENSMODP00000006129 Pfam PF00046 IPR001356 247 303 1.20e-21 Homeobox domain
ENSMODP00000006129 Pfam PF10525 IPR019549 304 330 5.30e-16 Homeobox engrailed, C-terminal
ENSMODP00000006129 PRINTS PR00024 IPR020479 268 279 2.40e-06 Homeodomain, metazoa
ENSMODP00000006129 PRINTS PR00024 IPR020479 283 293 2.40e-06 Homeodomain, metazoa
ENSMODP00000006129 PRINTS PR00024 IPR020479 293 302 2.40e-06 Homeodomain, metazoa
ENSMODP00000006129 PRINTS PR00026 IPR000747 245 262 7.70e-18 Homeodomain engrailed
ENSMODP00000006129 PRINTS PR00026 IPR000747 308 325 7.70e-18 Homeodomain engrailed
ENSMODP00000006129 ProSitePatterns PS00027 IPR017970 279 302 - Homeobox, conserved site
ENSMODP00000006129 ProSitePatterns PS00033 IPR019737 315 322 - Homeobox engrailed-type, conserved site
ENSMODP00000006129 ProSiteProfiles PS50071 IPR001356 244 304 0.00e-00 Homeobox domain
ENSMODP00000006129 SMART SM00389 IPR001356 246 308 7.10e-28 Homeobox domain
ENSMODP00000006129 SUPERFAMILY SSF46689 IPR009057 237 303 0.00e-00 Homeodomain-like

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSMODP00000006129 PF00046 8.3e-22 Homeobox Homeobox domain
ENSMODP00000006129 PF10525 2.7e-16 Engrail_1_C_sig Engrailed homeobox C-terminal signature domain
ENSMODP00000006129 PF07941 0.00099 K_channel_TID Potassium channel Kv1.4 tandem inactivation domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSMODP00000006129 GO:0005634 cellular_component nucleus
ENSMODP00000006129 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
61853 Nomascus leucogenys 100581025 30195 Bombus terrestris 100649797
8128 Oreochromis niloticus 100706716 132113 Bombus impatiens 100743858
143995 Megachile rotundata 100882481 34638 Metaseiulus occidentalis 100908620
9597 Pan paniscus 100996220 9555 Papio anubis 101019723
7897 Latimeria chalumnae 102360063 7227 Drosophila melanogaster 36240
7719 Ciona intestinalis 445653 9544 Macaca mulatta 716307
7460 Apis mellifera 725151 9615 Canis familiaris ENSCAFG00000005082
9483 Callithrix jacchus ENSCJAG00000017450 51511 Ciona savignyi ENSCSAVG00000008099
7955 Danio rerio ENSDARG00000038868 9796 Equus caballus ENSECAG00000021744
69293 Gasterosteus aculeatus ENSGACG00000003888 8049 Gadus morhua ENSGMOG00000004983
9785 Loxodonta africana ENSLAFG00000032115 9103 Meleagris gallopavo ENSMGAG00000012331
7425 Nasonia vitripennis 100123905 10224 Saccoglossus kowalevskii 100303466
9601 Pongo abelii 100459532 9823 Sus scrofa 100512078
7463 Apis florea 100870890 30611 Otolemur garnettii 100946410
31033 Takifugu rubripes 101068755 43179 Ictidomys tridecemlineatus 101960578
8083 Xiphophorus maculatus 102234767 9606 Homo sapiens 2020
7668 Strongylocentrotus purpuratus 590038 7070 Tribolium castaneum 661645
28377 Anolis carolinensis ENSACAG00000011018 9646 Ailuropoda melanoleuca ENSAMEG00000001224
9913 Bos taurus ENSBTAG00000018917 10141 Cavia porcellus ENSCPOG00000024572
9365 Erinaceus europaeus ENSEEUG00000004213 9371 Echinops telfairi ENSETEG00000004995
9685 Felis catus ENSFCAG00000023560 9595 Gorilla gorilla ENSGGOG00000022981
59463 Myotis lucifugus ENSMLUG00000004165 9669 Mustela putorius furo ENSMPUG00000009596
9258 Ornithorhynchus anatinus ENSOANG00000006149 8090 Oryzias latipes ENSORLG00000010437
7757 Petromyzon marinus ENSPMAG00000010362 13735 Pelodiscus sinensis ENSPSIG00000014871
59729 Taeniopygia guttata ENSTGUG00000000695 99883 Tetraodon nigroviridis ENSTNIG00000012777
9739 Tursiops truncatus ENSTTRG00000013702 9986 Oryctolagus cuniculus ENSOCUG00000002453
132908 Pteropus vampyrus ENSPVAG00000003106