Basic Information
Gene ID 100582446
Gene Name HIF3A
Full Name Uncharacterized protein
Organism Nomascus leucogenys [61853]

Cross Reference
UniProt G1QQE6 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSNLEP00000003164 Pfam PF00989 IPR013767 92 146 9.80e-07 PAS fold
ENSNLEP00000003164 Pfam PF11413 IPR021537 478 509 5.40e-15 Hypoxia-inducible factor, alpha subunit
ENSNLEP00000003164 ProSiteProfiles PS50112 IPR000014 246 297 0.00e-00 PAS domain
ENSNLEP00000003164 ProSiteProfiles PS50112 IPR000014 90 154 0.00e-00 PAS domain
ENSNLEP00000003164 ProSiteProfiles PS50888 IPR011598 14 67 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
ENSNLEP00000003164 SMART SM00086 IPR001610 301 344 1.20e-04 PAC motif
ENSNLEP00000003164 SMART SM00091 IPR000014 227 295 2.80e-05 PAS domain
ENSNLEP00000003164 SMART SM00091 IPR000014 84 150 1.10e-12 PAS domain
ENSNLEP00000003164 SMART SM00353 IPR011598 20 75 5.40e-10 Myc-type, basic helix-loop-helix (bHLH) domain
ENSNLEP00000003164 SUPERFAMILY SSF47459 IPR011598 14 70 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
ENSNLEP00000003164 SUPERFAMILY SSF55785 IPR000014 241 341 0.00e-00 PAS domain
ENSNLEP00000003164 SUPERFAMILY SSF55785 IPR000014 93 156 0.00e-00 PAS domain
ENSNLEP00000003164 TIGRFAM TIGR00229 IPR000014 248 324 5.90e-06 PAS domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSNLEP00000003164 PF14598 3.3e-22 PAS_11 PAS domain
ENSNLEP00000003164 PF08447 9.4e-21 PAS_3 PAS fold
ENSNLEP00000003164 PF00989 1.8e-15 PAS PAS fold
ENSNLEP00000003164 PF11413 2.8e-15 HIF-1 Hypoxia-inducible factor-1
ENSNLEP00000003164 PF13426 2.8e-09 PAS_9 PAS domain
ENSNLEP00000003164 PF08448 8.7e-08 PAS_4 PAS fold

Gene Ontology Annotation
Protein Entry Name Space Description
ENSNLEP00000003164 GO:0001666 biological_process response to hypoxia
ENSNLEP00000003164 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSNLEP00000003164 GO:0071456 biological_process cellular response to hypoxia
ENSNLEP00000003164 GO:0005634 cellular_component nucleus
ENSNLEP00000003164 GO:0005737 cellular_component cytoplasm
ENSNLEP00000003164 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSNLEP00000003164 GO:0004871 molecular_function signal transducer activity
ENSNLEP00000003164 GO:0035035 molecular_function histone acetyltransferase binding
ENSNLEP00000003164 GO:0046983 molecular_function protein dimerization activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9483 Callithrix jacchus 100411678 7029 Acyrthosiphon pisum 100167974
10224 Saccoglossus kowalevskii 100329032 8128 Oreochromis niloticus 100708832
9555 Papio anubis 101007659 39432 Saimiri boliviensis 101027930
9595 Gorilla gorilla 101146641 43179 Ictidomys tridecemlineatus 101976940
13735 Pelodiscus sinensis 102457736 7955 Danio rerio 393202
9615 Canis familiaris 480348 10090 Mus musculus 53417
7668 Strongylocentrotus purpuratus 577801 9606 Homo sapiens 64344
28377 Anolis carolinensis ENSACAG00000016766 9646 Ailuropoda melanoleuca ENSAMEG00000008615
10141 Cavia porcellus ENSCPOG00000024199 51511 Ciona savignyi ENSCSAVG00000005768
10020 Dipodomys ordii ENSDORG00000004664 9796 Equus caballus ENSECAG00000020693
9365 Erinaceus europaeus ENSEEUG00000009703 9685 Felis catus ENSFCAG00000014181
69293 Gasterosteus aculeatus ENSGACG00000013185 9031 Gallus gallus ENSGALG00000011870
9315 Macropus eugenii ENSMEUG00000002474 30608 Microcebus murinus ENSMICG00000016033
59463 Myotis lucifugus ENSMLUG00000014423 13616 Monodelphis domestica ENSMODG00000008760
9669 Mustela putorius furo ENSMPUG00000005285 9978 Ochotona princeps ENSOPRG00000014480
8090 Oryzias latipes ENSORLG00000002004 9813 Procavia capensis ENSPCAG00000006067
7757 Petromyzon marinus ENSPMAG00000009272 9601 Pongo abelii ENSPPYG00000010147
132908 Pteropus vampyrus ENSPVAG00000003553 10116 Rattus norvegicus ENSRNOG00000017198
9823 Sus scrofa ENSSSCG00000003101 37347 Tupaia belangeri ENSTBEG00000002129
59729 Taeniopygia guttata ENSTGUG00000012978 99883 Tetraodon nigroviridis ENSTNIG00000006798
9478 Tarsius syrichta ENSTSYG00000009179 8364 Xenopus tropicalis ENSXETG00000014449
9597 Pan paniscus 100979253 7897 Latimeria chalumnae 102348279
9598 Pan troglodytes 456149 7070 Tribolium castaneum 655772
9913 Bos taurus ENSBTAG00000003711 9358 Choloepus hoffmanni ENSCHOG00000005351
9361 Dasypus novemcinctus ENSDNOG00000005938 8049 Gadus morhua ENSGMOG00000016337
9785 Loxodonta africana ENSLAFG00000017230 9103 Meleagris gallopavo ENSMGAG00000013552
9544 Macaca mulatta ENSMMUG00000023326 9258 Ornithorhynchus anatinus ENSOANG00000009092
9986 Oryctolagus cuniculus ENSOCUG00000017741 30611 Otolemur garnettii ENSOGAG00000008187
42254 Sorex araneus ENSSARG00000011198 9305 Sarcophilus harrisii ENSSHAG00000004128
31033 Takifugu rubripes ENSTRUG00000008563 9739 Tursiops truncatus ENSTTRG00000001609
30538 Vicugna pacos ENSVPAG00000002395 8083 Xiphophorus maculatus ENSXMAG00000003186