Basic Information
Gene ID 53417 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name Hif3a; Mop7
Full Name Hypoxia-inducible factor 3-alpha
Organism Mus musculus [10090]

Cross Reference
UniProt Q0VBL6 UniGene Mm.135110
PDB NULL OMIM NULL
KEGG mmu:53417 UCSC uc009fir.2

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSMUSP00000104132 Pfam PF00989 IPR013767 92 146 9.60e-07 PAS fold
ENSMUSP00000104132 Pfam PF11413 IPR021537 475 506 1.40e-15 Hypoxia-inducible factor, alpha subunit
ENSMUSP00000104132 ProSiteProfiles PS50112 IPR000014 246 297 0.00e-00 PAS domain
ENSMUSP00000104132 ProSiteProfiles PS50112 IPR000014 90 145 0.00e-00 PAS domain
ENSMUSP00000104132 ProSiteProfiles PS50888 IPR011598 14 67 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
ENSMUSP00000104132 SMART SM00086 IPR001610 301 344 8.70e-05 PAC motif
ENSMUSP00000104132 SMART SM00091 IPR000014 227 295 1.00e-05 PAS domain
ENSMUSP00000104132 SMART SM00091 IPR000014 84 150 3.80e-12 PAS domain
ENSMUSP00000104132 SMART SM00353 IPR011598 20 75 5.40e-10 Myc-type, basic helix-loop-helix (bHLH) domain
ENSMUSP00000104132 SUPERFAMILY SSF47459 IPR011598 13 71 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
ENSMUSP00000104132 SUPERFAMILY SSF55785 IPR000014 241 341 0.00e-00 PAS domain
ENSMUSP00000104132 SUPERFAMILY SSF55785 IPR000014 93 145 0.00e-00 PAS domain
ENSMUSP00000104132 TIGRFAM TIGR00229 IPR000014 248 324 9.20e-06 PAS domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSMUSP00000104132 PF14598 7e-21 PAS_11 PAS domain
ENSMUSP00000104132 PF08447 9.6e-21 PAS_3 PAS fold
ENSMUSP00000104132 PF11413 7.1e-16 HIF-1 Hypoxia-inducible factor-1
ENSMUSP00000104132 PF00989 2.3e-15 PAS PAS fold
ENSMUSP00000104132 PF13426 4.5e-09 PAS_9 PAS domain
ENSMUSP00000104132 PF08448 2.2e-08 PAS_4 PAS fold

Gene Ontology Annotation
Protein Entry Name Space Description
ENSMUSP00000104132 GO:0001666 biological_process response to hypoxia
ENSMUSP00000104132 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSMUSP00000104132 GO:0071456 biological_process cellular response to hypoxia
ENSMUSP00000104132 GO:0005634 cellular_component nucleus
ENSMUSP00000104132 GO:0005737 cellular_component cytoplasm
ENSMUSP00000104132 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSMUSP00000104132 GO:0004871 molecular_function signal transducer activity
ENSMUSP00000104132 GO:0035035 molecular_function histone acetyltransferase binding
ENSMUSP00000104132 GO:0046983 molecular_function protein dimerization activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7425 Nasonia vitripennis 100117407 7029 Acyrthosiphon pisum 100167974
9483 Callithrix jacchus 100411678 61853 Nomascus leucogenys 100582446
30195 Bombus terrestris 100648501 8128 Oreochromis niloticus 100708832
132113 Bombus impatiens 100742767 10029 Cricetulus griseus 100770497
7463 Apis florea 100863085 34638 Metaseiulus occidentalis 100905945
9597 Pan paniscus 100979253 9555 Papio anubis 101007659
9595 Gorilla gorilla 101146641 43179 Ictidomys tridecemlineatus 101976940
7897 Latimeria chalumnae 102357464 13735 Pelodiscus sinensis 102457736
7955 Danio rerio 393202 7460 Apis mellifera 410669
9598 Pan troglodytes 456149 9615 Canis familiaris 480348
10224 Saccoglossus kowalevskii 100329032 143995 Megachile rotundata 100878780
39432 Saimiri boliviensis 101027930 9606 Homo sapiens 64344
9478 Tarsius syrichta ENSTSYG00000009179 7668 Strongylocentrotus purpuratus 577801
7070 Tribolium castaneum 655772 28377 Anolis carolinensis ENSACAG00000016766
9646 Ailuropoda melanoleuca ENSAMEG00000008615 9913 Bos taurus ENSBTAG00000003711
9358 Choloepus hoffmanni ENSCHOG00000005351 7719 Ciona intestinalis ENSCING00000001010
10141 Cavia porcellus ENSCPOG00000024199 51511 Ciona savignyi ENSCSAVG00000005768
9361 Dasypus novemcinctus ENSDNOG00000005938 10020 Dipodomys ordii ENSDORG00000004664
9796 Equus caballus ENSECAG00000020693 9365 Erinaceus europaeus ENSEEUG00000009703
9371 Echinops telfairi ENSETEG00000012055 9685 Felis catus ENSFCAG00000014181
69293 Gasterosteus aculeatus ENSGACG00000013185 9031 Gallus gallus ENSGALG00000011870
8049 Gadus morhua ENSGMOG00000016337 9785 Loxodonta africana ENSLAFG00000017230
9315 Macropus eugenii ENSMEUG00000002474 9103 Meleagris gallopavo ENSMGAG00000013552
30608 Microcebus murinus ENSMICG00000002949 59463 Myotis lucifugus ENSMLUG00000014423
9544 Macaca mulatta ENSMMUG00000023326 13616 Monodelphis domestica ENSMODG00000008760
9669 Mustela putorius furo ENSMPUG00000005285 9258 Ornithorhynchus anatinus ENSOANG00000009092
9986 Oryctolagus cuniculus ENSOCUG00000017741 30611 Otolemur garnettii ENSOGAG00000008187
9978 Ochotona princeps ENSOPRG00000014480 8090 Oryzias latipes ENSORLG00000002004
9813 Procavia capensis ENSPCAG00000006067 7757 Petromyzon marinus ENSPMAG00000009272
9601 Pongo abelii ENSPPYG00000010147 132908 Pteropus vampyrus ENSPVAG00000003553
10116 Rattus norvegicus ENSRNOG00000017198 42254 Sorex araneus ENSSARG00000011198
9305 Sarcophilus harrisii ENSSHAG00000004128 9823 Sus scrofa ENSSSCG00000003101
37347 Tupaia belangeri ENSTBEG00000002129 59729 Taeniopygia guttata ENSTGUG00000012978
99883 Tetraodon nigroviridis ENSTNIG00000006798 31033 Takifugu rubripes ENSTRUG00000008563
9739 Tursiops truncatus ENSTTRG00000001609 30538 Vicugna pacos ENSVPAG00000002395
8364 Xenopus tropicalis ENSXETG00000014449 8083 Xiphophorus maculatus ENSXMAG00000003186
7227 Drosophila melanogaster FBgn0004666