Basic Information
Gene ID 8022 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name LHX3
Full Name LIM/homeobox protein Lhx3
Organism Homo sapiens [9606]

Cross Reference
UniProt Q9UBR4 UniGene Hs.148427
PDB NULL OMIM 600577
KEGG hsa:8022 UCSC uc004cha.3

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING 9606.ENSP00000360811

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000360811 Gene3D G3DSA:1.10.10.60 IPR009057 164 226 5.80e-23 Homeodomain-like
ENSP00000360811 Gene3D G3DSA:2.10.110.10 IPR001781 100 151 2.40e-14 Zinc finger, LIM-type
ENSP00000360811 Gene3D G3DSA:2.10.110.10 IPR001781 34 99 5.20e-17 Zinc finger, LIM-type
ENSP00000360811 Pfam PF00046 IPR001356 163 219 1.40e-20 Homeobox domain
ENSP00000360811 Pfam PF00412 IPR001781 36 91 4.00e-15 Zinc finger, LIM-type
ENSP00000360811 Pfam PF00412 IPR001781 95 152 6.00e-16 Zinc finger, LIM-type
ENSP00000360811 ProSitePatterns PS00027 IPR017970 195 218 - Homeobox, conserved site
ENSP00000360811 ProSitePatterns PS00478 IPR001781 36 70 - Zinc finger, LIM-type
ENSP00000360811 ProSitePatterns PS00478 IPR001781 95 130 - Zinc finger, LIM-type
ENSP00000360811 ProSiteProfiles PS50023 IPR001781 34 93 0.00e-00 Zinc finger, LIM-type
ENSP00000360811 ProSiteProfiles PS50023 IPR001781 94 156 0.00e-00 Zinc finger, LIM-type
ENSP00000360811 ProSiteProfiles PS50071 IPR001356 160 220 0.00e-00 Homeobox domain
ENSP00000360811 SMART SM00132 IPR001781 35 86 5.40e-20 Zinc finger, LIM-type
ENSP00000360811 SMART SM00132 IPR001781 94 149 3.10e-19 Zinc finger, LIM-type
ENSP00000360811 SMART SM00389 IPR001356 162 224 2.80e-25 Homeobox domain
ENSP00000360811 SUPERFAMILY SSF46689 IPR009057 159 222 0.00e-00 Homeodomain-like

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000360811 PF00412 1.8e-31 LIM LIM domain
ENSP00000360811 PF00046 7.2e-21 Homeobox Homeobox domain
ENSP00000360811 PF05920 0.00072 Homeobox_KN Homeobox KN domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000360811 GO:0005634 cellular_component nucleus
ENSP00000360811 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSP00000360811 GO:0008270 molecular_function zinc ion binding
ENSP00000360811 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
13616 Monodelphis domestica 100016250 9785 Loxodonta africana 100657028
8083 Xiphophorus maculatus 102236864 9913 Bos taurus 539213
9598 Pan troglodytes 746333 7029 Acyrthosiphon pisum 100164426
10224 Saccoglossus kowalevskii 100303523 9601 Pongo abelii 100442936
400682 Amphimedon queenslandica 100634938 8128 Oreochromis niloticus 100693378
10029 Cricetulus griseus 100758218 34638 Metaseiulus occidentalis 100903153
9305 Sarcophilus harrisii 100929025 30611 Otolemur garnettii 100944641
9597 Pan paniscus 100973066 9555 Papio anubis 100999398
39432 Saimiri boliviensis 101040320 31033 Takifugu rubripes 101064401
6239 Caenorhabditis elegans 181012 7227 Drosophila melanogaster 35184
9646 Ailuropoda melanoleuca ENSAMEG00000003556 7719 Ciona intestinalis ENSCING00000009072
9796 Equus caballus ENSECAG00000021983 9365 Erinaceus europaeus ENSEEUG00000014517
7897 Latimeria chalumnae ENSLACG00000016988 9315 Macropus eugenii ENSMEUG00000008096
8090 Oryzias latipes ENSORLG00000006699 13735 Pelodiscus sinensis ENSPSIG00000008129
59729 Taeniopygia guttata ENSTGUG00000006385 99883 Tetraodon nigroviridis ENSTNIG00000018735
9739 Tursiops truncatus ENSTTRG00000007569 8364 Xenopus tropicalis ENSXETG00000000726
28377 Anolis carolinensis ENSACAG00000015639 9615 Canis familiaris ENSCAFG00000019695
69293 Gasterosteus aculeatus ENSGACG00000016592 8049 Gadus morhua ENSGMOG00000015270
9103 Meleagris gallopavo ENSMGAG00000003074 9813 Procavia capensis ENSPCAG00000016565
132908 Pteropus vampyrus ENSPVAG00000002969 43179 Ictidomys tridecemlineatus ENSSTOG00000005001