Basic Information
Gene ID ENSONIG00000013354
Gene Name ER
Full Name Estrogen receptor
Organism Oreochromis niloticus [8128]

Cross Reference
UniProt I3K6P3 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSONIP00000016788 Gene3D G3DSA:1.10.565.10 IPR008946 240 270 3.60e-84 Nuclear hormone receptor, ligand-binding
ENSONIP00000016788 Gene3D G3DSA:1.10.565.10 IPR008946 314 551 3.60e-84 Nuclear hormone receptor, ligand-binding
ENSONIP00000016788 Gene3D G3DSA:3.30.50.10 IPR013088 186 239 1.10e-27 Zinc finger, NHR/GATA-type
ENSONIP00000016788 Pfam PF00104 IPR000536 340 527 2.10e-29 Nuclear hormone receptor, ligand-binding, core
ENSONIP00000016788 Pfam PF00105 IPR001628 185 253 3.40e-31 Zinc finger, nuclear hormone receptor-type
ENSONIP00000016788 Pfam PF02159 IPR001292 48 181 4.30e-34 Oestrogen receptor
ENSONIP00000016788 PIRSF PIRSF002527 IPR024178 54 628 9.00e-304 Oestrogen receptor/oestrogen-related receptor
ENSONIP00000016788 PIRSF PIRSF500101 IPR001292 1 632 0.00e-00 Oestrogen receptor
ENSONIP00000016788 PRINTS PR00047 IPR001628 186 202 9.70e-17 Zinc finger, nuclear hormone receptor-type
ENSONIP00000016788 PRINTS PR00047 IPR001628 202 217 9.70e-17 Zinc finger, nuclear hormone receptor-type
ENSONIP00000016788 PRINTS PR00047 IPR001628 235 243 9.70e-17 Zinc finger, nuclear hormone receptor-type
ENSONIP00000016788 PRINTS PR00047 IPR001628 243 251 9.70e-17 Zinc finger, nuclear hormone receptor-type
ENSONIP00000016788 PRINTS PR00398 IPR001723 247 257 4.60e-27 Steroid hormone receptor
ENSONIP00000016788 PRINTS PR00398 IPR001723 352 373 4.60e-27 Steroid hormone receptor
ENSONIP00000016788 PRINTS PR00398 IPR001723 373 389 4.60e-27 Steroid hormone receptor
ENSONIP00000016788 PRINTS PR00398 IPR001723 441 456 4.60e-27 Steroid hormone receptor
ENSONIP00000016788 PRINTS PR00398 IPR001723 509 526 4.60e-27 Steroid hormone receptor
ENSONIP00000016788 ProSitePatterns PS00031 IPR001628 186 212 - Zinc finger, nuclear hormone receptor-type
ENSONIP00000016788 ProSiteProfiles PS51030 IPR001628 183 258 0.00e-00 Zinc finger, nuclear hormone receptor-type
ENSONIP00000016788 SMART SM00399 IPR001628 183 254 6.60e-40 Zinc finger, nuclear hormone receptor-type
ENSONIP00000016788 SMART SM00430 IPR000536 351 521 3.90e-36 Nuclear hormone receptor, ligand-binding, core
ENSONIP00000016788 SUPERFAMILY SSF48508 IPR008946 313 550 0.00e-00 Nuclear hormone receptor, ligand-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSONIP00000016788 PF02159 4.3e-34 Oest_recep Oestrogen receptor
ENSONIP00000016788 PF00105 1.4e-31 zf-C4 Zinc finger, C4 type (two domains)
ENSONIP00000016788 PF00104 1.3e-29 Hormone_recep Ligand-binding domain of nuclear hormone receptor

Gene Ontology Annotation
Protein Entry Name Space Description
ENSONIP00000016788 GO:0006351 biological_process transcription, DNA-templated
ENSONIP00000016788 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSONIP00000016788 GO:0043401 biological_process steroid hormone mediated signaling pathway
ENSONIP00000016788 GO:0005634 cellular_component nucleus
ENSONIP00000016788 GO:0003677 molecular_function DNA binding
ENSONIP00000016788 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSONIP00000016788 GO:0003707 molecular_function steroid hormone receptor activity
ENSONIP00000016788 GO:0005496 molecular_function steroid binding
ENSONIP00000016788 GO:0008270 molecular_function zinc ion binding
ENSONIP00000016788 GO:0008289 molecular_function lipid binding
ENSONIP00000016788 GO:0030284 molecular_function estrogen receptor activity
ENSONIP00000016788 GO:0043565 molecular_function sequence-specific DNA binding
ENSONIP00000016788 GO:0046872 molecular_function metal ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9555 Papio anubis 100303417 9986 Oryctolagus cuniculus 100351261
9615 Canis familiaris 403640 9913 Bos taurus ENSBTAG00000007159
9595 Gorilla gorilla ENSGGOG00000009678 8049 Gadus morhua ENSGMOG00000014898
9315 Macropus eugenii ENSMEUG00000003564 13616 Monodelphis domestica 100027187
9483 Callithrix jacchus 100385918 9103 Meleagris gallopavo 100542782
61853 Nomascus leucogenys 100580202 10141 Cavia porcellus 100713276
10029 Cricetulus griseus 100768474 9597 Pan paniscus 100980011
9669 Mustela putorius furo 101690352 8083 Xiphophorus maculatus 102235986
13735 Pelodiscus sinensis 102456765 10090 Mus musculus 13982
9606 Homo sapiens 2099 28377 Anolis carolinensis ENSACAG00000006213
7955 Danio rerio ENSDARG00000004111 69293 Gasterosteus aculeatus ENSGACG00000008711
9031 Gallus gallus ENSGALG00000012973 59463 Myotis lucifugus ENSMLUG00000014181
30611 Otolemur garnettii ENSOGAG00000012580 8090 Oryzias latipes ENSORLG00000014514
99883 Tetraodon nigroviridis ENSTNIG00000012264 31033 Takifugu rubripes ENSTRUG00000018219
9478 Tarsius syrichta ENSTSYG00000006280 9739 Tursiops truncatus ENSTTRG00000002996
8364 Xenopus tropicalis ENSXETG00000012364 9978 Ochotona princeps ENSOPRG00000012663
132908 Pteropus vampyrus ENSPVAG00000001923 43179 Ictidomys tridecemlineatus ENSSTOG00000006748
59729 Taeniopygia guttata ENSTGUG00000011249