Basic Information
Gene ID ENSTNIG00000012264
Gene Name ESR1
Full Name Estrogen receptor
Organism Tetraodon nigroviridis [99883]

Cross Reference
UniProt H3D3Z3 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSTNIP00000015231 Gene3D G3DSA:1.10.565.10 IPR008946 249 280 4.90e-85 Nuclear hormone receptor, ligand-binding
ENSTNIP00000015231 Gene3D G3DSA:1.10.565.10 IPR008946 325 561 4.90e-85 Nuclear hormone receptor, ligand-binding
ENSTNIP00000015231 Gene3D G3DSA:3.30.50.10 IPR013088 190 248 8.20e-29 Zinc finger, NHR/GATA-type
ENSTNIP00000015231 Pfam PF00104 IPR000536 353 538 6.30e-30 Nuclear hormone receptor, ligand-binding, core
ENSTNIP00000015231 Pfam PF00105 IPR001628 191 259 6.10e-31 Zinc finger, nuclear hormone receptor-type
ENSTNIP00000015231 Pfam PF02159 IPR001292 48 188 8.00e-34 Oestrogen receptor
ENSTNIP00000015231 PIRSF PIRSF002527 IPR024178 54 621 1.10e-297 Oestrogen receptor/oestrogen-related receptor
ENSTNIP00000015231 PIRSF PIRSF500101 IPR001292 1 625 0.00e-00 Oestrogen receptor
ENSTNIP00000015231 PRINTS PR00047 IPR001628 192 208 9.40e-17 Zinc finger, nuclear hormone receptor-type
ENSTNIP00000015231 PRINTS PR00047 IPR001628 208 223 9.40e-17 Zinc finger, nuclear hormone receptor-type
ENSTNIP00000015231 PRINTS PR00047 IPR001628 241 249 9.40e-17 Zinc finger, nuclear hormone receptor-type
ENSTNIP00000015231 PRINTS PR00047 IPR001628 249 257 9.40e-17 Zinc finger, nuclear hormone receptor-type
ENSTNIP00000015231 PRINTS PR00398 IPR001723 262 272 6.80e-26 Steroid hormone receptor
ENSTNIP00000015231 PRINTS PR00398 IPR001723 363 384 6.80e-26 Steroid hormone receptor
ENSTNIP00000015231 PRINTS PR00398 IPR001723 384 400 6.80e-26 Steroid hormone receptor
ENSTNIP00000015231 PRINTS PR00398 IPR001723 452 467 6.80e-26 Steroid hormone receptor
ENSTNIP00000015231 PRINTS PR00398 IPR001723 520 537 6.80e-26 Steroid hormone receptor
ENSTNIP00000015231 ProSitePatterns PS00031 IPR001628 192 218 - Zinc finger, nuclear hormone receptor-type
ENSTNIP00000015231 ProSiteProfiles PS51030 IPR001628 189 264 0.00e-00 Zinc finger, nuclear hormone receptor-type
ENSTNIP00000015231 SMART SM00399 IPR001628 189 260 4.10e-38 Zinc finger, nuclear hormone receptor-type
ENSTNIP00000015231 SMART SM00430 IPR000536 362 532 1.10e-38 Nuclear hormone receptor, ligand-binding, core
ENSTNIP00000015231 SUPERFAMILY SSF48508 IPR008946 324 561 0.00e-00 Nuclear hormone receptor, ligand-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSTNIP00000015231 PF02159 3.1e-34 Oest_recep Oestrogen receptor
ENSTNIP00000015231 PF00105 3.4e-31 zf-C4 Zinc finger, C4 type (two domains)
ENSTNIP00000015231 PF00104 4.1e-30 Hormone_recep Ligand-binding domain of nuclear hormone receptor

Gene Ontology Annotation
Protein Entry Name Space Description
ENSTNIP00000015231 GO:0006351 biological_process transcription, DNA-templated
ENSTNIP00000015231 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSTNIP00000015231 GO:0043401 biological_process steroid hormone mediated signaling pathway
ENSTNIP00000015231 GO:0005634 cellular_component nucleus
ENSTNIP00000015231 GO:0003677 molecular_function DNA binding
ENSTNIP00000015231 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSTNIP00000015231 GO:0003707 molecular_function steroid hormone receptor activity
ENSTNIP00000015231 GO:0005496 molecular_function steroid binding
ENSTNIP00000015231 GO:0008270 molecular_function zinc ion binding
ENSTNIP00000015231 GO:0008289 molecular_function lipid binding
ENSTNIP00000015231 GO:0030284 molecular_function estrogen receptor activity
ENSTNIP00000015231 GO:0043565 molecular_function sequence-specific DNA binding
ENSTNIP00000015231 GO:0046872 molecular_function metal ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
13616 Monodelphis domestica 100027187 9555 Papio anubis 100303417
9986 Oryctolagus cuniculus 100351261 9597 Pan paniscus 100980011
9615 Canis familiaris 403640 28377 Anolis carolinensis ENSACAG00000006213
9913 Bos taurus ENSBTAG00000007159 10020 Dipodomys ordii ENSDORG00000010443
9796 Equus caballus ENSECAG00000022441 9595 Gorilla gorilla ENSGGOG00000009678
8049 Gadus morhua ENSGMOG00000014898 9315 Macropus eugenii ENSMEUG00000003564
8128 Oreochromis niloticus ENSONIG00000013354 9978 Ochotona princeps ENSOPRG00000012663
132908 Pteropus vampyrus ENSPVAG00000001923 43179 Ictidomys tridecemlineatus ENSSTOG00000006748
37347 Tupaia belangeri ENSTBEG00000005946 59729 Taeniopygia guttata ENSTGUG00000011249
9483 Callithrix jacchus 100385918 9103 Meleagris gallopavo 100542782
61853 Nomascus leucogenys 100580202 10141 Cavia porcellus 100713276
10029 Cricetulus griseus 100768474 9669 Mustela putorius furo 101690352
8083 Xiphophorus maculatus 102235986 13735 Pelodiscus sinensis 102456765
10090 Mus musculus 13982 9606 Homo sapiens 2099
9646 Ailuropoda melanoleuca ENSAMEG00000011072 7955 Danio rerio ENSDARG00000004111
9685 Felis catus ENSFCAG00000031492 69293 Gasterosteus aculeatus ENSGACG00000008711
9031 Gallus gallus ENSGALG00000012973 59463 Myotis lucifugus ENSMLUG00000014181
30611 Otolemur garnettii ENSOGAG00000012580 8090 Oryzias latipes ENSORLG00000014514
31033 Takifugu rubripes ENSTRUG00000018219 9478 Tarsius syrichta ENSTSYG00000006280
9739 Tursiops truncatus ENSTTRG00000002996 8364 Xenopus tropicalis ENSXETG00000012364