Basic Information
Gene ID 100768474
Gene Name Esr1
Full Name PREDICTED: estrogen receptor [Cricetulus griseus].
Organism Cricetulus griseus [10029]

Cross Reference
UniProt NULL UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
XP_003495923 Gene3D G3DSA:1.10.565.10 IPR008946 239 269 5.00e-100 Nuclear hormone receptor, ligand-binding
XP_003495923 Gene3D G3DSA:1.10.565.10 IPR008946 311 548 5.00e-100 Nuclear hormone receptor, ligand-binding
XP_003495923 Gene3D G3DSA:3.30.50.10 IPR013088 185 238 9.60e-28 Zinc finger, NHR/GATA-type
XP_003495923 Pfam PF00104 IPR000536 328 524 5.40e-29 Nuclear hormone receptor, ligand-binding, core
XP_003495923 Pfam PF00105 IPR001628 184 252 2.20e-31 Zinc finger, nuclear hormone receptor-type
XP_003495923 Pfam PF02159 IPR001292 42 181 7.40e-55 Oestrogen receptor
XP_003495923 Pfam PF12743 IPR024736 552 595 5.30e-20 Oestrogen-type nuclear receptor final C-terminal domain
XP_003495923 PIRSF PIRSF002527 IPR024178 42 590 3.00e-303 Oestrogen receptor/oestrogen-related receptor
XP_003495923 PIRSF PIRSF500101 IPR001292 1 595 0.00e-00 Oestrogen receptor
XP_003495923 PRINTS PR00047 IPR001628 185 201 8.20e-17 Zinc finger, nuclear hormone receptor-type
XP_003495923 PRINTS PR00047 IPR001628 201 216 8.20e-17 Zinc finger, nuclear hormone receptor-type
XP_003495923 PRINTS PR00047 IPR001628 234 242 8.20e-17 Zinc finger, nuclear hormone receptor-type
XP_003495923 PRINTS PR00047 IPR001628 242 250 8.20e-17 Zinc finger, nuclear hormone receptor-type
XP_003495923 PRINTS PR00398 IPR001723 246 256 1.70e-26 Steroid hormone receptor
XP_003495923 PRINTS PR00398 IPR001723 349 370 1.70e-26 Steroid hormone receptor
XP_003495923 PRINTS PR00398 IPR001723 370 386 1.70e-26 Steroid hormone receptor
XP_003495923 PRINTS PR00398 IPR001723 438 453 1.70e-26 Steroid hormone receptor
XP_003495923 PRINTS PR00398 IPR001723 506 523 1.70e-26 Steroid hormone receptor
XP_003495923 PRINTS PR00543 IPR001292 115 131 4.70e-83 Oestrogen receptor
XP_003495923 PRINTS PR00543 IPR001292 132 151 4.70e-83 Oestrogen receptor
XP_003495923 PRINTS PR00543 IPR001292 153 172 4.70e-83 Oestrogen receptor
XP_003495923 PRINTS PR00543 IPR001292 26 43 4.70e-83 Oestrogen receptor
XP_003495923 PRINTS PR00543 IPR001292 45 62 4.70e-83 Oestrogen receptor
XP_003495923 PRINTS PR00543 IPR001292 6 24 4.70e-83 Oestrogen receptor
XP_003495923 PRINTS PR00543 IPR001292 69 84 4.70e-83 Oestrogen receptor
XP_003495923 PRINTS PR00543 IPR001292 96 110 4.70e-83 Oestrogen receptor
XP_003495923 ProSitePatterns PS00031 IPR001628 185 211 - Zinc finger, nuclear hormone receptor-type
XP_003495923 ProSiteProfiles PS51030 IPR001628 182 257 0.00e-00 Zinc finger, nuclear hormone receptor-type
XP_003495923 SMART SM00399 IPR001628 182 253 6.40e-40 Zinc finger, nuclear hormone receptor-type
XP_003495923 SMART SM00430 IPR000536 348 518 4.20e-38 Nuclear hormone receptor, ligand-binding, core
XP_003495923 SUPERFAMILY SSF48508 IPR008946 235 261 0.00e-00 Nuclear hormone receptor, ligand-binding
XP_003495923 SUPERFAMILY SSF48508 IPR008946 302 547 0.00e-00 Nuclear hormone receptor, ligand-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
XP_003495923 PF02159 0 Oest_recep Oestrogen receptor
XP_003495923 PF00105 1.3e-31 zf-C4 Zinc finger, C4 type (two domains)
XP_003495923 PF00104 3.3e-29 Hormone_recep Ligand-binding domain of nuclear hormone receptor
XP_003495923 PF12743 2.7e-20 ESR1_C Oestrogen-type nuclear receptor final C-terminal

Gene Ontology Annotation
Protein Entry Name Space Description
XP_003495923 GO:0006351 biological_process transcription, DNA-templated
XP_003495923 GO:0006355 biological_process regulation of transcription, DNA-templated
XP_003495923 GO:0007200 biological_process phospholipase C-activating G-protein coupled receptor signaling pathway
XP_003495923 GO:0007204 biological_process positive regulation of cytosolic calcium ion concentration
XP_003495923 GO:0010863 biological_process positive regulation of phospholipase C activity
XP_003495923 GO:0030518 biological_process intracellular steroid hormone receptor signaling pathway
XP_003495923 GO:0043124 biological_process negative regulation of I-kappaB kinase/NF-kappaB signaling
XP_003495923 GO:0043433 biological_process negative regulation of sequence-specific DNA binding transcription factor activity
XP_003495923 GO:0045429 biological_process positive regulation of nitric oxide biosynthetic process
XP_003495923 GO:0051000 biological_process positive regulation of nitric-oxide synthase activity
XP_003495923 GO:0051091 biological_process positive regulation of sequence-specific DNA binding transcription factor activity
XP_003495923 GO:0071392 biological_process cellular response to estradiol stimulus
XP_003495923 GO:0005634 cellular_component nucleus
XP_003495923 GO:0005794 cellular_component Golgi apparatus
XP_003495923 GO:0005886 cellular_component plasma membrane
XP_003495923 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
XP_003495923 GO:0003707 molecular_function steroid hormone receptor activity
XP_003495923 GO:0005496 molecular_function steroid binding
XP_003495923 GO:0008270 molecular_function zinc ion binding
XP_003495923 GO:0030284 molecular_function estrogen receptor activity
XP_003495923 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
13616 Monodelphis domestica 100027187 7425 Nasonia vitripennis 100120388
9555 Papio anubis 100303417 9986 Oryctolagus cuniculus 100351261
61853 Nomascus leucogenys 100580202 9483 Callithrix jacchus 100385918
9103 Meleagris gallopavo 100542782 30195 Bombus terrestris 100644400
10141 Cavia porcellus 100713276 132113 Bombus impatiens 100747415
34638 Metaseiulus occidentalis 100897394 39432 Saimiri boliviensis 101034130
9669 Mustela putorius furo 101690352 8083 Xiphophorus maculatus 102235986
13735 Pelodiscus sinensis 102456765 9606 Homo sapiens 2099
7227 Drosophila melanogaster 38912 7070 Tribolium castaneum 654940
9646 Ailuropoda melanoleuca ENSAMEG00000011072 9371 Echinops telfairi ENSETEG00000006131
9685 Felis catus ENSFCAG00000031492 69293 Gasterosteus aculeatus ENSGACG00000008711
9031 Gallus gallus ENSGALG00000012973 30608 Microcebus murinus ENSMICG00000007592
59463 Myotis lucifugus ENSMLUG00000014181 8090 Oryzias latipes ENSORLG00000014514
42254 Sorex araneus ENSSARG00000004419 31033 Takifugu rubripes ENSTRUG00000018219
9478 Tarsius syrichta ENSTSYG00000006280 9739 Tursiops truncatus ENSTTRG00000002996
8364 Xenopus tropicalis ENSXETG00000012364 7463 Apis florea 100863304
143995 Megachile rotundata 100882199 9597 Pan paniscus 100980011
10090 Mus musculus 13982 9615 Canis familiaris 403640
7460 Apis mellifera 408855 28377 Anolis carolinensis ENSACAG00000006213
9913 Bos taurus ENSBTAG00000007159 7719 Ciona intestinalis ENSCING00000018200
51511 Ciona savignyi ENSCSAVG00000002034 7955 Danio rerio ENSDARG00000004111
10020 Dipodomys ordii ENSDORG00000010443 9796 Equus caballus ENSECAG00000022441
9365 Erinaceus europaeus ENSEEUG00000000828 9595 Gorilla gorilla ENSGGOG00000009678
8049 Gadus morhua ENSGMOG00000014898 9315 Macropus eugenii ENSMEUG00000003564
9258 Ornithorhynchus anatinus ENSOANG00000015561 30611 Otolemur garnettii ENSOGAG00000012580
8128 Oreochromis niloticus ENSONIG00000013354 9978 Ochotona princeps ENSOPRG00000012663
132908 Pteropus vampyrus ENSPVAG00000001923 10116 Rattus norvegicus ENSRNOG00000019358
43179 Ictidomys tridecemlineatus ENSSTOG00000006748 37347 Tupaia belangeri ENSTBEG00000005946
59729 Taeniopygia guttata ENSTGUG00000011249 99883 Tetraodon nigroviridis ENSTNIG00000012264
30538 Vicugna pacos ENSVPAG00000001185