Basic Information
Gene ID ENSSARG00000004419
Gene Name ENSSARG00000004419
Full Name ENSSARG00000004419
Organism Sorex araneus [42254]

Cross Reference
UniProt NULL UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSSARP00000004001 Gene3D G3DSA:1.10.565.10 IPR008946 240 270 2.90e-53 Nuclear hormone receptor, ligand-binding
ENSSARP00000004001 Gene3D G3DSA:1.10.565.10 IPR008946 311 410 2.90e-53 Nuclear hormone receptor, ligand-binding
ENSSARP00000004001 Gene3D G3DSA:3.30.50.10 IPR013088 188 239 1.20e-15 Zinc finger, NHR/GATA-type
ENSSARP00000004001 Pfam PF00104 IPR000536 328 409 1.10e-13 Nuclear hormone receptor, ligand-binding, core
ENSSARP00000004001 Pfam PF00105 IPR001628 187 253 7.00e-20 Zinc finger, nuclear hormone receptor-type
ENSSARP00000004001 Pfam PF02159 IPR001292 43 184 5.60e-45 Oestrogen receptor
ENSSARP00000004001 PRINTS PR00398 IPR001723 247 257 4.80e-15 Steroid hormone receptor
ENSSARP00000004001 PRINTS PR00398 IPR001723 349 370 4.80e-15 Steroid hormone receptor
ENSSARP00000004001 PRINTS PR00398 IPR001723 370 386 4.80e-15 Steroid hormone receptor
ENSSARP00000004001 PRINTS PR00543 IPR001292 100 114 1.90e-41 Oestrogen receptor
ENSSARP00000004001 PRINTS PR00543 IPR001292 118 134 1.90e-41 Oestrogen receptor
ENSSARP00000004001 PRINTS PR00543 IPR001292 135 154 1.90e-41 Oestrogen receptor
ENSSARP00000004001 PRINTS PR00543 IPR001292 156 175 1.90e-41 Oestrogen receptor
ENSSARP00000004001 PRINTS PR00543 IPR001292 6 24 1.90e-41 Oestrogen receptor
ENSSARP00000004001 PRINTS PR00543 IPR001292 72 87 1.90e-41 Oestrogen receptor
ENSSARP00000004001 ProSiteProfiles PS51030 IPR001628 185 258 0.00e-00 Zinc finger, nuclear hormone receptor-type
ENSSARP00000004001 SMART SM00399 IPR001628 185 254 6.60e-17 Zinc finger, nuclear hormone receptor-type
ENSSARP00000004001 SUPERFAMILY SSF48508 IPR008946 236 262 0.00e-00 Nuclear hormone receptor, ligand-binding
ENSSARP00000004001 SUPERFAMILY SSF48508 IPR008946 302 410 0.00e-00 Nuclear hormone receptor, ligand-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSSARP00000004001 PF02159 5.60519e-45 Oest_recep Oestrogen receptor
ENSSARP00000004001 PF00105 4.8e-20 zf-C4 Zinc finger, C4 type (two domains)
ENSSARP00000004001 PF00104 8.1e-14 Hormone_recep Ligand-binding domain of nuclear hormone receptor

Gene Ontology Annotation
Protein Entry Name Space Description
ENSSARP00000004001 GO:0006351 biological_process transcription, DNA-templated
ENSSARP00000004001 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSSARP00000004001 GO:0007200 biological_process phospholipase C-activating G-protein coupled receptor signaling pathway
ENSSARP00000004001 GO:0007204 biological_process positive regulation of cytosolic calcium ion concentration
ENSSARP00000004001 GO:0010863 biological_process positive regulation of phospholipase C activity
ENSSARP00000004001 GO:0030518 biological_process intracellular steroid hormone receptor signaling pathway
ENSSARP00000004001 GO:0043124 biological_process negative regulation of I-kappaB kinase/NF-kappaB signaling
ENSSARP00000004001 GO:0043433 biological_process negative regulation of sequence-specific DNA binding transcription factor activity
ENSSARP00000004001 GO:0045429 biological_process positive regulation of nitric oxide biosynthetic process
ENSSARP00000004001 GO:0051000 biological_process positive regulation of nitric-oxide synthase activity
ENSSARP00000004001 GO:0051091 biological_process positive regulation of sequence-specific DNA binding transcription factor activity
ENSSARP00000004001 GO:0071392 biological_process cellular response to estradiol stimulus
ENSSARP00000004001 GO:0005634 cellular_component nucleus
ENSSARP00000004001 GO:0005794 cellular_component Golgi apparatus
ENSSARP00000004001 GO:0005886 cellular_component plasma membrane
ENSSARP00000004001 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSSARP00000004001 GO:0003707 molecular_function steroid hormone receptor activity
ENSSARP00000004001 GO:0005496 molecular_function steroid binding
ENSSARP00000004001 GO:0008270 molecular_function zinc ion binding
ENSSARP00000004001 GO:0030284 molecular_function estrogen receptor activity
ENSSARP00000004001 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
13616 Monodelphis domestica 100027187 9555 Papio anubis 100303417
9986 Oryctolagus cuniculus 100351261 61853 Nomascus leucogenys 100580202
10029 Cricetulus griseus 100768474 9597 Pan paniscus 100980011
39432 Saimiri boliviensis 101040869 13735 Pelodiscus sinensis 102456765
10090 Mus musculus 13982 9615 Canis familiaris 403640
28377 Anolis carolinensis ENSACAG00000006213 9913 Bos taurus ENSBTAG00000007159
10020 Dipodomys ordii ENSDORG00000010443 9796 Equus caballus ENSECAG00000022441
9365 Erinaceus europaeus ENSEEUG00000000828 9685 Felis catus ENSFCAG00000031492
9595 Gorilla gorilla ENSGGOG00000009678 9315 Macropus eugenii ENSMEUG00000003564
30608 Microcebus murinus ENSMICG00000007592 9258 Ornithorhynchus anatinus ENSOANG00000003331
30611 Otolemur garnettii ENSOGAG00000012580 9978 Ochotona princeps ENSOPRG00000012663
9813 Procavia capensis ENSPCAG00000015346 132908 Pteropus vampyrus ENSPVAG00000001923
10116 Rattus norvegicus ENSRNOG00000019358 9483 Callithrix jacchus 100385918
9103 Meleagris gallopavo 100542782 10141 Cavia porcellus 100713276
9669 Mustela putorius furo 101690352 9606 Homo sapiens 2099
9646 Ailuropoda melanoleuca ENSAMEG00000011072 9371 Echinops telfairi ENSETEG00000006131
9031 Gallus gallus ENSGALG00000012973 59463 Myotis lucifugus ENSMLUG00000014181
8364 Xenopus tropicalis ENSXETG00000012364 9823 Sus scrofa ENSSSCG00000004084
43179 Ictidomys tridecemlineatus ENSSTOG00000006748 37347 Tupaia belangeri ENSTBEG00000005946
59729 Taeniopygia guttata ENSTGUG00000011249 9478 Tarsius syrichta ENSTSYG00000006280
9739 Tursiops truncatus ENSTTRG00000002996 30538 Vicugna pacos ENSVPAG00000001185