Basic Information
Gene ID ENSECAG00000008126
Gene Name TP53
Full Name Cellular tumor antigen p53
Organism Equus caballus [9796]

Cross Reference
UniProt F6TL72 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSECAP00000006210 Gene3D G3DSA:2.60.40.720 IPR012346 1 171 1.50e-84 p53/RUNT-type transcription factor, DNA-binding domain
ENSECAP00000006210 Gene3D G3DSA:4.10.170.10 IPR010991 195 235 4.30e-21 p53, tetramerisation domain
ENSECAP00000006210 PANTHER PTHR11447 IPR002117 1 269 0.00e-00 p53 tumour suppressor family
ENSECAP00000006210 Pfam PF00870 IPR011615 1 164 5.40e-94 p53, DNA-binding domain
ENSECAP00000006210 Pfam PF07710 IPR010991 195 234 2.80e-19 p53, tetramerisation domain
ENSECAP00000006210 PRINTS PR00386 IPR002117 112 134 1.20e-70 p53 tumour suppressor family
ENSECAP00000006210 PRINTS PR00386 IPR002117 140 162 1.20e-70 p53 tumour suppressor family
ENSECAP00000006210 PRINTS PR00386 IPR002117 202 226 1.20e-70 p53 tumour suppressor family
ENSECAP00000006210 PRINTS PR00386 IPR002117 33 54 1.20e-70 p53 tumour suppressor family
ENSECAP00000006210 PRINTS PR00386 IPR002117 89 110 1.20e-70 p53 tumour suppressor family
ENSECAP00000006210 ProSitePatterns PS00348 IPR002117 113 125 - p53 tumour suppressor family
ENSECAP00000006210 SUPERFAMILY SSF47719 IPR010991 195 233 0.00e-00 p53, tetramerisation domain
ENSECAP00000006210 SUPERFAMILY SSF49417 IPR008967 1 163 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSECAP00000006210 PF00870 0 P53 P53 DNA-binding domain
ENSECAP00000006210 PF07710 1.3e-19 P53_tetramer P53 tetramerisation motif

Gene Ontology Annotation
Protein Entry Name Space Description
ENSECAP00000006210 GO:0000733 biological_process DNA strand renaturation
ENSECAP00000006210 GO:0006289 biological_process nucleotide-excision repair
ENSECAP00000006210 GO:0006351 biological_process transcription, DNA-templated
ENSECAP00000006210 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSECAP00000006210 GO:0006915 biological_process apoptotic process
ENSECAP00000006210 GO:0007049 biological_process cell cycle
ENSECAP00000006210 GO:0007275 biological_process multicellular organismal development
ENSECAP00000006210 GO:0007569 biological_process cell aging
ENSECAP00000006210 GO:0012501 biological_process programmed cell death
ENSECAP00000006210 GO:0030308 biological_process negative regulation of cell growth
ENSECAP00000006210 GO:0051262 biological_process protein tetramerization
ENSECAP00000006210 GO:0090200 biological_process positive regulation of release of cytochrome c from mitochondria
ENSECAP00000006210 GO:0097252 biological_process oligodendrocyte apoptotic process
ENSECAP00000006210 GO:0005634 cellular_component nucleus
ENSECAP00000006210 GO:0005730 cellular_component nucleolus
ENSECAP00000006210 GO:0005737 cellular_component cytoplasm
ENSECAP00000006210 GO:0005739 cellular_component mitochondrion
ENSECAP00000006210 GO:0005759 cellular_component mitochondrial matrix
ENSECAP00000006210 GO:0005783 cellular_component endoplasmic reticulum
ENSECAP00000006210 GO:0003677 molecular_function DNA binding
ENSECAP00000006210 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSECAP00000006210 GO:0005507 molecular_function copper ion binding
ENSECAP00000006210 GO:0005524 molecular_function ATP binding
ENSECAP00000006210 GO:0044212 molecular_function transcription regulatory region DNA binding
ENSECAP00000006210 GO:0046872 molecular_function metal ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
10029 Cricetulus griseus 100682525 9305 Sarcophilus harrisii 100922473
9597 Pan paniscus 100973941 39432 Saimiri boliviensis 101043647
9615 Canis familiaris ENSCAFG00000016714 10141 Cavia porcellus 100379269
9483 Callithrix jacchus 100415710 9601 Pongo abelii 100435218
9555 Papio anubis 101006608 9595 Gorilla gorilla 101133524
43179 Ictidomys tridecemlineatus 101957738 13735 Pelodiscus sinensis 102448135
10116 Rattus norvegicus 24842 9598 Pan troglodytes 455214
9685 Felis catus 493847 9606 Homo sapiens 7157
9361 Dasypus novemcinctus ENSDNOG00000005252 9365 Erinaceus europaeus ENSEEUG00000014573
9315 Macropus eugenii ENSMEUG00000013135 59463 Myotis lucifugus ENSMLUG00000006411
9669 Mustela putorius furo ENSMPUG00000009017 9813 Procavia capensis ENSPCAG00000012725
132908 Pteropus vampyrus ENSPVAG00000016317 42254 Sorex araneus ENSSARG00000006206
9739 Tursiops truncatus ENSTTRG00000010250 9371 Echinops telfairi ENSETEG00000008987
7897 Latimeria chalumnae ENSLACG00000014014 9785 Loxodonta africana ENSLAFG00000007483
30608 Microcebus murinus ENSMICG00000014853 61853 Nomascus leucogenys ENSNLEG00000009730
9986 Oryctolagus cuniculus ENSOCUG00000001138 30611 Otolemur garnettii ENSOGAG00000016871
9978 Ochotona princeps ENSOPRG00000006441 37347 Tupaia belangeri ENSTBEG00000011771