Basic Information
Gene ID ENSLACG00000014014
Gene Name NULL
Full Name Cellular tumor antigen p53
Organism Latimeria chalumnae [7897]

Cross Reference
UniProt H3B1Z4 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSLACP00000015915 Gene3D G3DSA:2.60.40.720 IPR012346 101 303 1.00e-91 p53/RUNT-type transcription factor, DNA-binding domain
ENSLACP00000015915 Gene3D G3DSA:4.10.170.10 IPR010991 331 366 6.90e-16 p53, tetramerisation domain
ENSLACP00000015915 PANTHER PTHR11447 IPR002117 1 398 0.00e-00 p53 tumour suppressor family
ENSLACP00000015915 Pfam PF00870 IPR011615 101 295 2.60e-108 p53, DNA-binding domain
ENSLACP00000015915 Pfam PF07710 IPR010991 325 366 9.60e-17 p53, tetramerisation domain
ENSLACP00000015915 Pfam PF08563 IPR013872 12 26 1.70e-06 p53 transactivation domain
ENSLACP00000015915 PRINTS PR00386 IPR002117 122 148 6.60e-81 p53 tumour suppressor family
ENSLACP00000015915 PRINTS PR00386 IPR002117 164 185 6.60e-81 p53 tumour suppressor family
ENSLACP00000015915 PRINTS PR00386 IPR002117 220 241 6.60e-81 p53 tumour suppressor family
ENSLACP00000015915 PRINTS PR00386 IPR002117 243 265 6.60e-81 p53 tumour suppressor family
ENSLACP00000015915 PRINTS PR00386 IPR002117 271 293 6.60e-81 p53 tumour suppressor family
ENSLACP00000015915 PRINTS PR00386 IPR002117 334 358 6.60e-81 p53 tumour suppressor family
ENSLACP00000015915 ProSitePatterns PS00348 IPR002117 244 256 - p53 tumour suppressor family
ENSLACP00000015915 SUPERFAMILY SSF47719 IPR010991 330 364 0.00e-00 p53, tetramerisation domain
ENSLACP00000015915 SUPERFAMILY SSF49417 IPR008967 103 294 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSLACP00000015915 PF00870 0 P53 P53 DNA-binding domain
ENSLACP00000015915 PF07710 4.9e-17 P53_tetramer P53 tetramerisation motif
ENSLACP00000015915 PF08563 8.7e-07 P53_TAD P53 transactivation motif

Gene Ontology Annotation
Protein Entry Name Space Description
ENSLACP00000015915 GO:0000733 biological_process DNA strand renaturation
ENSLACP00000015915 GO:0006289 biological_process nucleotide-excision repair
ENSLACP00000015915 GO:0006351 biological_process transcription, DNA-templated
ENSLACP00000015915 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSLACP00000015915 GO:0006915 biological_process apoptotic process
ENSLACP00000015915 GO:0007049 biological_process cell cycle
ENSLACP00000015915 GO:0007275 biological_process multicellular organismal development
ENSLACP00000015915 GO:0007569 biological_process cell aging
ENSLACP00000015915 GO:0012501 biological_process programmed cell death
ENSLACP00000015915 GO:0030308 biological_process negative regulation of cell growth
ENSLACP00000015915 GO:0051262 biological_process protein tetramerization
ENSLACP00000015915 GO:0090200 biological_process positive regulation of release of cytochrome c from mitochondria
ENSLACP00000015915 GO:0097252 biological_process oligodendrocyte apoptotic process
ENSLACP00000015915 GO:0005634 cellular_component nucleus
ENSLACP00000015915 GO:0005730 cellular_component nucleolus
ENSLACP00000015915 GO:0005737 cellular_component cytoplasm
ENSLACP00000015915 GO:0005739 cellular_component mitochondrion
ENSLACP00000015915 GO:0005759 cellular_component mitochondrial matrix
ENSLACP00000015915 GO:0005783 cellular_component endoplasmic reticulum
ENSLACP00000015915 GO:0003677 molecular_function DNA binding
ENSLACP00000015915 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSLACP00000015915 GO:0005507 molecular_function copper ion binding
ENSLACP00000015915 GO:0005524 molecular_function ATP binding
ENSLACP00000015915 GO:0044212 molecular_function transcription regulatory region DNA binding
ENSLACP00000015915 GO:0046872 molecular_function metal ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9305 Sarcophilus harrisii 100922473 9597 Pan paniscus 100973941
9615 Canis familiaris ENSCAFG00000016714 10141 Cavia porcellus 100379269
9483 Callithrix jacchus 100415710 9601 Pongo abelii 100435218
10029 Cricetulus griseus 100682525 8128 Oreochromis niloticus 100702587
143995 Megachile rotundata 100880552 9555 Papio anubis 101006608
39432 Saimiri boliviensis 101043647 9595 Gorilla gorilla 101133524
43179 Ictidomys tridecemlineatus 101957738 13735 Pelodiscus sinensis 102448135
10116 Rattus norvegicus 24842 9598 Pan troglodytes 455214
9685 Felis catus 493847 9606 Homo sapiens 7157
9361 Dasypus novemcinctus ENSDNOG00000005252 9796 Equus caballus ENSECAG00000008126
9365 Erinaceus europaeus ENSEEUG00000014573 9371 Echinops telfairi ENSETEG00000008987
9785 Loxodonta africana ENSLAFG00000007483 9315 Macropus eugenii ENSMEUG00000013135
30608 Microcebus murinus ENSMICG00000014853 59463 Myotis lucifugus ENSMLUG00000006411
9669 Mustela putorius furo ENSMPUG00000009017 9978 Ochotona princeps ENSOPRG00000006441
9813 Procavia capensis ENSPCAG00000012725 42254 Sorex araneus ENSSARG00000006206
37347 Tupaia belangeri ENSTBEG00000011771 9739 Tursiops truncatus ENSTTRG00000010250
8364 Xenopus tropicalis ENSXETG00000025055 61853 Nomascus leucogenys ENSNLEG00000009730
9986 Oryctolagus cuniculus ENSOCUG00000001138 30611 Otolemur garnettii ENSOGAG00000016871