Basic Information
Gene ID ENSOCUG00000001138
Gene Name TP53
Full Name Cellular tumor antigen p53
Organism Oryctolagus cuniculus [9986]

Cross Reference
UniProt G1SEU0 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSOCUP00000000989 Gene3D G3DSA:2.60.40.720 IPR012346 91 292 1.10e-96 p53/RUNT-type transcription factor, DNA-binding domain
ENSOCUP00000000989 Gene3D G3DSA:4.10.170.10 IPR010991 317 357 7.90e-20 p53, tetramerisation domain
ENSOCUP00000000989 PANTHER PTHR11447 IPR002117 1 391 0.00e-00 p53 tumour suppressor family
ENSOCUP00000000989 Pfam PF00870 IPR011615 92 285 1.10e-109 p53, DNA-binding domain
ENSOCUP00000000989 Pfam PF07710 IPR010991 317 356 4.80e-18 p53, tetramerisation domain
ENSOCUP00000000989 Pfam PF08563 IPR013872 5 29 1.20e-10 p53 transactivation domain
ENSOCUP00000000989 PRINTS PR00386 IPR002117 113 139 7.50e-87 p53 tumour suppressor family
ENSOCUP00000000989 PRINTS PR00386 IPR002117 155 176 7.50e-87 p53 tumour suppressor family
ENSOCUP00000000989 PRINTS PR00386 IPR002117 210 231 7.50e-87 p53 tumour suppressor family
ENSOCUP00000000989 PRINTS PR00386 IPR002117 233 255 7.50e-87 p53 tumour suppressor family
ENSOCUP00000000989 PRINTS PR00386 IPR002117 261 283 7.50e-87 p53 tumour suppressor family
ENSOCUP00000000989 PRINTS PR00386 IPR002117 324 348 7.50e-87 p53 tumour suppressor family
ENSOCUP00000000989 ProSitePatterns PS00348 IPR002117 234 246 - p53 tumour suppressor family
ENSOCUP00000000989 SUPERFAMILY SSF47719 IPR010991 317 356 0.00e-00 p53, tetramerisation domain
ENSOCUP00000000989 SUPERFAMILY SSF49417 IPR008967 94 284 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSOCUP00000000989 PF00870 0 P53 P53 DNA-binding domain
ENSOCUP00000000989 PF07710 2.4e-18 P53_tetramer P53 tetramerisation motif
ENSOCUP00000000989 PF08563 5.2e-11 P53_TAD P53 transactivation motif

Gene Ontology Annotation
Protein Entry Name Space Description
ENSOCUP00000000989 GO:0000733 biological_process DNA strand renaturation
ENSOCUP00000000989 GO:0006289 biological_process nucleotide-excision repair
ENSOCUP00000000989 GO:0006351 biological_process transcription, DNA-templated
ENSOCUP00000000989 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSOCUP00000000989 GO:0006915 biological_process apoptotic process
ENSOCUP00000000989 GO:0007049 biological_process cell cycle
ENSOCUP00000000989 GO:0007275 biological_process multicellular organismal development
ENSOCUP00000000989 GO:0007569 biological_process cell aging
ENSOCUP00000000989 GO:0012501 biological_process programmed cell death
ENSOCUP00000000989 GO:0030308 biological_process negative regulation of cell growth
ENSOCUP00000000989 GO:0051262 biological_process protein tetramerization
ENSOCUP00000000989 GO:0090200 biological_process positive regulation of release of cytochrome c from mitochondria
ENSOCUP00000000989 GO:0097252 biological_process oligodendrocyte apoptotic process
ENSOCUP00000000989 GO:0005634 cellular_component nucleus
ENSOCUP00000000989 GO:0005730 cellular_component nucleolus
ENSOCUP00000000989 GO:0005737 cellular_component cytoplasm
ENSOCUP00000000989 GO:0005739 cellular_component mitochondrion
ENSOCUP00000000989 GO:0005759 cellular_component mitochondrial matrix
ENSOCUP00000000989 GO:0005783 cellular_component endoplasmic reticulum
ENSOCUP00000000989 GO:0003677 molecular_function DNA binding
ENSOCUP00000000989 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSOCUP00000000989 GO:0005507 molecular_function copper ion binding
ENSOCUP00000000989 GO:0005524 molecular_function ATP binding
ENSOCUP00000000989 GO:0044212 molecular_function transcription regulatory region DNA binding
ENSOCUP00000000989 GO:0046872 molecular_function metal ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
10141 Cavia porcellus 100379269 9483 Callithrix jacchus 100415710
9601 Pongo abelii 100435218 10029 Cricetulus griseus 100682525
8128 Oreochromis niloticus 100702587 9305 Sarcophilus harrisii 100922473
9597 Pan paniscus 100973941 9555 Papio anubis 101006608
39432 Saimiri boliviensis 101043647 9595 Gorilla gorilla 101133524
43179 Ictidomys tridecemlineatus 101957738 8083 Xiphophorus maculatus 102219062
13735 Pelodiscus sinensis 102448135 10116 Rattus norvegicus 24842
9598 Pan troglodytes 455214 9685 Felis catus 493847
9606 Homo sapiens 7157 9615 Canis familiaris ENSCAFG00000016714
9361 Dasypus novemcinctus ENSDNOG00000005252 9796 Equus caballus ENSECAG00000008126
9365 Erinaceus europaeus ENSEEUG00000014573 9371 Echinops telfairi ENSETEG00000008987
7897 Latimeria chalumnae ENSLACG00000014014 9785 Loxodonta africana ENSLAFG00000007483
9315 Macropus eugenii ENSMEUG00000013135 30608 Microcebus murinus ENSMICG00000014853
59463 Myotis lucifugus ENSMLUG00000006411 9669 Mustela putorius furo ENSMPUG00000009017
61853 Nomascus leucogenys ENSNLEG00000009730 30611 Otolemur garnettii ENSOGAG00000016871
9978 Ochotona princeps ENSOPRG00000006441 9813 Procavia capensis ENSPCAG00000012725
132908 Pteropus vampyrus ENSPVAG00000016317 42254 Sorex araneus ENSSARG00000006206
37347 Tupaia belangeri ENSTBEG00000011771 9739 Tursiops truncatus ENSTTRG00000010250
8364 Xenopus tropicalis ENSXETG00000025055

Paralogs
ENSOCUG00000022109