Basic Information | |||
Gene ID | ENSOCUG00000001138 | ||
Gene Name | TP53 | ||
Full Name | Cellular tumor antigen p53 | ||
Organism | Oryctolagus cuniculus [9986] |
Cross Reference | |||
UniProt | G1SEU0 | UniGene | NULL |
PDB | NULL | OMIM | NULL |
KEGG | NULL | UCSC | NULL |
Protein Interactions | |
DIP | NULL |
IntAct | NULL |
MINT | NULL |
STRING | NULL |
Ensembl/RefSeq | Transcript ID | Protein ID | Gene ID |
ENSEMBL | |||
ENSEMBL |
InterPro Annotation | |||||||
Protein | Program | Term | IPRS | Start | End | Score | Description |
ENSOCUP00000000989 | Gene3D | G3DSA:2.60.40.720 | IPR012346 | 91 | 292 | 1.10e-96 | p53/RUNT-type transcription factor, DNA-binding domain |
ENSOCUP00000000989 | Gene3D | G3DSA:4.10.170.10 | IPR010991 | 317 | 357 | 7.90e-20 | p53, tetramerisation domain |
ENSOCUP00000000989 | PANTHER | PTHR11447 | IPR002117 | 1 | 391 | 0.00e-00 | p53 tumour suppressor family |
ENSOCUP00000000989 | Pfam | PF00870 | IPR011615 | 92 | 285 | 1.10e-109 | p53, DNA-binding domain |
ENSOCUP00000000989 | Pfam | PF07710 | IPR010991 | 317 | 356 | 4.80e-18 | p53, tetramerisation domain |
ENSOCUP00000000989 | Pfam | PF08563 | IPR013872 | 5 | 29 | 1.20e-10 | p53 transactivation domain |
ENSOCUP00000000989 | PRINTS | PR00386 | IPR002117 | 113 | 139 | 7.50e-87 | p53 tumour suppressor family |
ENSOCUP00000000989 | PRINTS | PR00386 | IPR002117 | 155 | 176 | 7.50e-87 | p53 tumour suppressor family |
ENSOCUP00000000989 | PRINTS | PR00386 | IPR002117 | 210 | 231 | 7.50e-87 | p53 tumour suppressor family |
ENSOCUP00000000989 | PRINTS | PR00386 | IPR002117 | 233 | 255 | 7.50e-87 | p53 tumour suppressor family |
ENSOCUP00000000989 | PRINTS | PR00386 | IPR002117 | 261 | 283 | 7.50e-87 | p53 tumour suppressor family |
ENSOCUP00000000989 | PRINTS | PR00386 | IPR002117 | 324 | 348 | 7.50e-87 | p53 tumour suppressor family |
ENSOCUP00000000989 | ProSitePatterns | PS00348 | IPR002117 | 234 | 246 | - | p53 tumour suppressor family |
ENSOCUP00000000989 | SUPERFAMILY | SSF47719 | IPR010991 | 317 | 356 | 0.00e-00 | p53, tetramerisation domain |
ENSOCUP00000000989 | SUPERFAMILY | SSF49417 | IPR008967 | 94 | 284 | 0.00e-00 | p53-like transcription factor, DNA-binding |
Pfam Annotation | ||||
Protein | Pfam ID | E.value | Name | Description |
ENSOCUP00000000989 | PF00870 | 0 | P53 | P53 DNA-binding domain |
ENSOCUP00000000989 | PF07710 | 2.4e-18 | P53_tetramer | P53 tetramerisation motif |
ENSOCUP00000000989 | PF08563 | 5.2e-11 | P53_TAD | P53 transactivation motif |
Gene Ontology Annotation | |||
Protein | Entry | Name Space | Description |
ENSOCUP00000000989 | GO:0000733 | biological_process | DNA strand renaturation |
ENSOCUP00000000989 | GO:0006289 | biological_process | nucleotide-excision repair |
ENSOCUP00000000989 | GO:0006351 | biological_process | transcription, DNA-templated |
ENSOCUP00000000989 | GO:0006355 | biological_process | regulation of transcription, DNA-templated |
ENSOCUP00000000989 | GO:0006915 | biological_process | apoptotic process |
ENSOCUP00000000989 | GO:0007049 | biological_process | cell cycle |
ENSOCUP00000000989 | GO:0007275 | biological_process | multicellular organismal development |
ENSOCUP00000000989 | GO:0007569 | biological_process | cell aging |
ENSOCUP00000000989 | GO:0012501 | biological_process | programmed cell death |
ENSOCUP00000000989 | GO:0030308 | biological_process | negative regulation of cell growth |
ENSOCUP00000000989 | GO:0051262 | biological_process | protein tetramerization |
ENSOCUP00000000989 | GO:0090200 | biological_process | positive regulation of release of cytochrome c from mitochondria |
ENSOCUP00000000989 | GO:0097252 | biological_process | oligodendrocyte apoptotic process |
ENSOCUP00000000989 | GO:0005634 | cellular_component | nucleus |
ENSOCUP00000000989 | GO:0005730 | cellular_component | nucleolus |
ENSOCUP00000000989 | GO:0005737 | cellular_component | cytoplasm |
ENSOCUP00000000989 | GO:0005739 | cellular_component | mitochondrion |
ENSOCUP00000000989 | GO:0005759 | cellular_component | mitochondrial matrix |
ENSOCUP00000000989 | GO:0005783 | cellular_component | endoplasmic reticulum |
ENSOCUP00000000989 | GO:0003677 | molecular_function | DNA binding |
ENSOCUP00000000989 | GO:0003700 | molecular_function | sequence-specific DNA binding transcription factor activity |
ENSOCUP00000000989 | GO:0005507 | molecular_function | copper ion binding |
ENSOCUP00000000989 | GO:0005524 | molecular_function | ATP binding |
ENSOCUP00000000989 | GO:0044212 | molecular_function | transcription regulatory region DNA binding |
ENSOCUP00000000989 | GO:0046872 | molecular_function | metal ion binding |
Orthologs | |||||
TAXID | Organism | Gene ID | TAXID | Organism | Gene ID |
10141 | Cavia porcellus | 100379269 | 9483 | Callithrix jacchus | 100415710 |
9601 | Pongo abelii | 100435218 | 10029 | Cricetulus griseus | 100682525 |
8128 | Oreochromis niloticus | 100702587 | 9305 | Sarcophilus harrisii | 100922473 |
9597 | Pan paniscus | 100973941 | 9555 | Papio anubis | 101006608 |
39432 | Saimiri boliviensis | 101043647 | 9595 | Gorilla gorilla | 101133524 |
43179 | Ictidomys tridecemlineatus | 101957738 | 8083 | Xiphophorus maculatus | 102219062 |
13735 | Pelodiscus sinensis | 102448135 | 10116 | Rattus norvegicus | 24842 |
9598 | Pan troglodytes | 455214 | 9685 | Felis catus | 493847 |
9606 | Homo sapiens | 7157 | 9615 | Canis familiaris | ENSCAFG00000016714 |
9361 | Dasypus novemcinctus | ENSDNOG00000005252 | 9796 | Equus caballus | ENSECAG00000008126 |
9365 | Erinaceus europaeus | ENSEEUG00000014573 | 9371 | Echinops telfairi | ENSETEG00000008987 |
7897 | Latimeria chalumnae | ENSLACG00000014014 | 9785 | Loxodonta africana | ENSLAFG00000007483 |
9315 | Macropus eugenii | ENSMEUG00000013135 | 30608 | Microcebus murinus | ENSMICG00000014853 |
59463 | Myotis lucifugus | ENSMLUG00000006411 | 9669 | Mustela putorius furo | ENSMPUG00000009017 |
61853 | Nomascus leucogenys | ENSNLEG00000009730 | 30611 | Otolemur garnettii | ENSOGAG00000016871 |
9978 | Ochotona princeps | ENSOPRG00000006441 | 9813 | Procavia capensis | ENSPCAG00000012725 |
132908 | Pteropus vampyrus | ENSPVAG00000016317 | 42254 | Sorex araneus | ENSSARG00000006206 |
37347 | Tupaia belangeri | ENSTBEG00000011771 | 9739 | Tursiops truncatus | ENSTTRG00000010250 |
8364 | Xenopus tropicalis | ENSXETG00000025055 |
Paralogs | |||
ENSOCUG00000022109 |