Basic Information
Gene ID 101957738
Gene Name TP53
Full Name Cellular tumor antigen p53
Organism Ictidomys tridecemlineatus [43179]

Cross Reference
UniProt I3N5N2 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSSTOP00000019678 Gene3D G3DSA:2.60.40.720 IPR012346 92 292 4.00e-97 p53/RUNT-type transcription factor, DNA-binding domain
ENSSTOP00000019678 Gene3D G3DSA:4.10.170.10 IPR010991 317 357 3.00e-19 p53, tetramerisation domain
ENSSTOP00000019678 PANTHER PTHR11447 IPR002117 1 391 0.00e-00 p53 tumour suppressor family
ENSSTOP00000019678 Pfam PF00870 IPR011615 93 286 3.70e-110 p53, DNA-binding domain
ENSSTOP00000019678 Pfam PF07710 IPR010991 316 356 8.50e-19 p53, tetramerisation domain
ENSSTOP00000019678 Pfam PF08563 IPR013872 5 29 1.80e-11 p53 transactivation domain
ENSSTOP00000019678 PRINTS PR00386 IPR002117 114 140 1.70e-86 p53 tumour suppressor family
ENSSTOP00000019678 PRINTS PR00386 IPR002117 156 177 1.70e-86 p53 tumour suppressor family
ENSSTOP00000019678 PRINTS PR00386 IPR002117 211 232 1.70e-86 p53 tumour suppressor family
ENSSTOP00000019678 PRINTS PR00386 IPR002117 234 256 1.70e-86 p53 tumour suppressor family
ENSSTOP00000019678 PRINTS PR00386 IPR002117 262 284 1.70e-86 p53 tumour suppressor family
ENSSTOP00000019678 PRINTS PR00386 IPR002117 324 348 1.70e-86 p53 tumour suppressor family
ENSSTOP00000019678 ProSitePatterns PS00348 IPR002117 235 247 - p53 tumour suppressor family
ENSSTOP00000019678 SUPERFAMILY SSF47719 IPR010991 317 356 0.00e-00 p53, tetramerisation domain
ENSSTOP00000019678 SUPERFAMILY SSF49417 IPR008967 95 285 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSSTOP00000019678 PF00870 0 P53 P53 DNA-binding domain
ENSSTOP00000019678 PF07710 4.4e-19 P53_tetramer P53 tetramerisation motif
ENSSTOP00000019678 PF08563 1.8e-11 P53_TAD P53 transactivation motif

Gene Ontology Annotation
Protein Entry Name Space Description
ENSSTOP00000019678 GO:0000733 biological_process DNA strand renaturation
ENSSTOP00000019678 GO:0006289 biological_process nucleotide-excision repair
ENSSTOP00000019678 GO:0006351 biological_process transcription, DNA-templated
ENSSTOP00000019678 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSSTOP00000019678 GO:0006915 biological_process apoptotic process
ENSSTOP00000019678 GO:0007049 biological_process cell cycle
ENSSTOP00000019678 GO:0007275 biological_process multicellular organismal development
ENSSTOP00000019678 GO:0007569 biological_process cell aging
ENSSTOP00000019678 GO:0012501 biological_process programmed cell death
ENSSTOP00000019678 GO:0030308 biological_process negative regulation of cell growth
ENSSTOP00000019678 GO:0051262 biological_process protein tetramerization
ENSSTOP00000019678 GO:0090200 biological_process positive regulation of release of cytochrome c from mitochondria
ENSSTOP00000019678 GO:0097252 biological_process oligodendrocyte apoptotic process
ENSSTOP00000019678 GO:0005634 cellular_component nucleus
ENSSTOP00000019678 GO:0005730 cellular_component nucleolus
ENSSTOP00000019678 GO:0005737 cellular_component cytoplasm
ENSSTOP00000019678 GO:0005739 cellular_component mitochondrion
ENSSTOP00000019678 GO:0005759 cellular_component mitochondrial matrix
ENSSTOP00000019678 GO:0005783 cellular_component endoplasmic reticulum
ENSSTOP00000019678 GO:0003677 molecular_function DNA binding
ENSSTOP00000019678 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSSTOP00000019678 GO:0005507 molecular_function copper ion binding
ENSSTOP00000019678 GO:0005524 molecular_function ATP binding
ENSSTOP00000019678 GO:0044212 molecular_function transcription regulatory region DNA binding
ENSSTOP00000019678 GO:0046872 molecular_function metal ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
10029 Cricetulus griseus 100682525 9305 Sarcophilus harrisii 100922473
9597 Pan paniscus 100973941 39432 Saimiri boliviensis 101043647
10141 Cavia porcellus 100379269 9483 Callithrix jacchus 100415710
9601 Pongo abelii 100435218 8128 Oreochromis niloticus 100702587
9555 Papio anubis 101006608 9595 Gorilla gorilla 101133524
13735 Pelodiscus sinensis 102448135 10116 Rattus norvegicus 24842
9598 Pan troglodytes 455214 9685 Felis catus 493847
9606 Homo sapiens 7157 9361 Dasypus novemcinctus ENSDNOG00000005252
9365 Erinaceus europaeus ENSEEUG00000014573 9315 Macropus eugenii ENSMEUG00000013135
59463 Myotis lucifugus ENSMLUG00000006411 9669 Mustela putorius furo ENSMPUG00000009017
9813 Procavia capensis ENSPCAG00000012725 132908 Pteropus vampyrus ENSPVAG00000016317
42254 Sorex araneus ENSSARG00000006206 9739 Tursiops truncatus ENSTTRG00000010250
8364 Xenopus tropicalis ENSXETG00000025055 8083 Xiphophorus maculatus 102219062
9615 Canis familiaris ENSCAFG00000016714 9796 Equus caballus ENSECAG00000008126
9371 Echinops telfairi ENSETEG00000008987 7897 Latimeria chalumnae ENSLACG00000014014
9785 Loxodonta africana ENSLAFG00000007483 30608 Microcebus murinus ENSMICG00000014853
61853 Nomascus leucogenys ENSNLEG00000009730 9986 Oryctolagus cuniculus ENSOCUG00000001138
30611 Otolemur garnettii ENSOGAG00000016871 9978 Ochotona princeps ENSOPRG00000006441
37347 Tupaia belangeri ENSTBEG00000011771