Basic Information
Gene ID 100379269
Gene Name TP53
Full Name Cellular tumor antigen p53
Organism Cavia porcellus [10141]

Cross Reference
UniProt Q9WUR6 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING 10141.ENSCPOP00000012841

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSCPOP00000012841 Gene3D G3DSA:2.60.40.720 IPR012346 92 290 1.30e-95 p53/RUNT-type transcription factor, DNA-binding domain
ENSCPOP00000012841 Gene3D G3DSA:4.10.170.10 IPR010991 317 357 4.40e-18 p53, tetramerisation domain
ENSCPOP00000012841 PANTHER PTHR11447 IPR002117 1 391 0.00e-00 p53 tumour suppressor family
ENSCPOP00000012841 Pfam PF00870 IPR011615 93 286 7.70e-108 p53, DNA-binding domain
ENSCPOP00000012841 Pfam PF07710 IPR010991 316 356 7.90e-18 p53, tetramerisation domain
ENSCPOP00000012841 Pfam PF08563 IPR013872 6 29 1.00e-11 p53 transactivation domain
ENSCPOP00000012841 PRINTS PR00386 IPR002117 114 140 2.70e-84 p53 tumour suppressor family
ENSCPOP00000012841 PRINTS PR00386 IPR002117 156 177 2.70e-84 p53 tumour suppressor family
ENSCPOP00000012841 PRINTS PR00386 IPR002117 211 232 2.70e-84 p53 tumour suppressor family
ENSCPOP00000012841 PRINTS PR00386 IPR002117 234 256 2.70e-84 p53 tumour suppressor family
ENSCPOP00000012841 PRINTS PR00386 IPR002117 262 284 2.70e-84 p53 tumour suppressor family
ENSCPOP00000012841 PRINTS PR00386 IPR002117 324 348 2.70e-84 p53 tumour suppressor family
ENSCPOP00000012841 ProSitePatterns PS00348 IPR002117 235 247 - p53 tumour suppressor family
ENSCPOP00000012841 SUPERFAMILY SSF47719 IPR010991 317 356 0.00e-00 p53, tetramerisation domain
ENSCPOP00000012841 SUPERFAMILY SSF49417 IPR008967 95 285 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSCPOP00000012841 PF00870 0 P53 P53 DNA-binding domain
ENSCPOP00000012841 PF07710 4.1e-18 P53_tetramer P53 tetramerisation motif
ENSCPOP00000012841 PF08563 1e-11 P53_TAD P53 transactivation motif

Gene Ontology Annotation
Protein Entry Name Space Description
ENSCPOP00000012841 GO:0000733 biological_process DNA strand renaturation
ENSCPOP00000012841 GO:0006289 biological_process nucleotide-excision repair
ENSCPOP00000012841 GO:0006351 biological_process transcription, DNA-templated
ENSCPOP00000012841 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSCPOP00000012841 GO:0006915 biological_process apoptotic process
ENSCPOP00000012841 GO:0007049 biological_process cell cycle
ENSCPOP00000012841 GO:0007275 biological_process multicellular organismal development
ENSCPOP00000012841 GO:0007569 biological_process cell aging
ENSCPOP00000012841 GO:0012501 biological_process programmed cell death
ENSCPOP00000012841 GO:0030308 biological_process negative regulation of cell growth
ENSCPOP00000012841 GO:0051262 biological_process protein tetramerization
ENSCPOP00000012841 GO:0090200 biological_process positive regulation of release of cytochrome c from mitochondria
ENSCPOP00000012841 GO:0097252 biological_process oligodendrocyte apoptotic process
ENSCPOP00000012841 GO:0005634 cellular_component nucleus
ENSCPOP00000012841 GO:0005730 cellular_component nucleolus
ENSCPOP00000012841 GO:0005737 cellular_component cytoplasm
ENSCPOP00000012841 GO:0005739 cellular_component mitochondrion
ENSCPOP00000012841 GO:0005759 cellular_component mitochondrial matrix
ENSCPOP00000012841 GO:0005783 cellular_component endoplasmic reticulum
ENSCPOP00000012841 GO:0003677 molecular_function DNA binding
ENSCPOP00000012841 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSCPOP00000012841 GO:0005507 molecular_function copper ion binding
ENSCPOP00000012841 GO:0005524 molecular_function ATP binding
ENSCPOP00000012841 GO:0044212 molecular_function transcription regulatory region DNA binding
ENSCPOP00000012841 GO:0046872 molecular_function metal ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9483 Callithrix jacchus 100415710 9601 Pongo abelii 100435218
9555 Papio anubis 101006608 9595 Gorilla gorilla 101133524
9598 Pan troglodytes 455214 9685 Felis catus 493847
9365 Erinaceus europaeus ENSEEUG00000014573 132908 Pteropus vampyrus ENSPVAG00000016317
8364 Xenopus tropicalis ENSXETG00000025055 10029 Cricetulus griseus 100682525
8128 Oreochromis niloticus 100702587 9305 Sarcophilus harrisii 100922473
9597 Pan paniscus 100973941 39432 Saimiri boliviensis 101043647
43179 Ictidomys tridecemlineatus 101957738 8083 Xiphophorus maculatus 102219062
13735 Pelodiscus sinensis 102448135 10116 Rattus norvegicus 24842
9606 Homo sapiens 7157 9615 Canis familiaris ENSCAFG00000016714
9361 Dasypus novemcinctus ENSDNOG00000005252 9796 Equus caballus ENSECAG00000008126
9371 Echinops telfairi ENSETEG00000008987 7897 Latimeria chalumnae ENSLACG00000014014
9785 Loxodonta africana ENSLAFG00000007483 9315 Macropus eugenii ENSMEUG00000013135
30608 Microcebus murinus ENSMICG00000014853 59463 Myotis lucifugus ENSMLUG00000006411
9669 Mustela putorius furo ENSMPUG00000009017 61853 Nomascus leucogenys ENSNLEG00000009730
9986 Oryctolagus cuniculus ENSOCUG00000001138 30611 Otolemur garnettii ENSOGAG00000016871
9978 Ochotona princeps ENSOPRG00000006441 9813 Procavia capensis ENSPCAG00000012725
42254 Sorex araneus ENSSARG00000006206 37347 Tupaia belangeri ENSTBEG00000011771
99883 Tetraodon nigroviridis ENSTNIG00000010137 9739 Tursiops truncatus ENSTTRG00000010250