Basic Information
Gene ID ENSMPUG00000009017
Gene Name TP53
Full Name Cellular tumor antigen p53
Organism Mustela putorius furo [9669]

Cross Reference
UniProt M3YC88 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSMPUP00000008945 Gene3D G3DSA:2.60.40.720 IPR012346 76 277 6.60e-96 p53/RUNT-type transcription factor, DNA-binding domain
ENSMPUP00000008945 Gene3D G3DSA:4.10.170.10 IPR010991 301 341 9.40e-18 p53, tetramerisation domain
ENSMPUP00000008945 PANTHER PTHR11447 IPR002117 1 375 0.00e-00 p53 tumour suppressor family
ENSMPUP00000008945 Pfam PF00870 IPR011615 77 270 6.70e-108 p53, DNA-binding domain
ENSMPUP00000008945 Pfam PF07710 IPR010991 301 340 1.50e-16 p53, tetramerisation domain
ENSMPUP00000008945 Pfam PF08563 IPR013872 5 29 2.20e-11 p53 transactivation domain
ENSMPUP00000008945 PRINTS PR00386 IPR002117 139 160 6.00e-84 p53 tumour suppressor family
ENSMPUP00000008945 PRINTS PR00386 IPR002117 195 216 6.00e-84 p53 tumour suppressor family
ENSMPUP00000008945 PRINTS PR00386 IPR002117 218 240 6.00e-84 p53 tumour suppressor family
ENSMPUP00000008945 PRINTS PR00386 IPR002117 246 268 6.00e-84 p53 tumour suppressor family
ENSMPUP00000008945 PRINTS PR00386 IPR002117 308 332 6.00e-84 p53 tumour suppressor family
ENSMPUP00000008945 PRINTS PR00386 IPR002117 97 123 6.00e-84 p53 tumour suppressor family
ENSMPUP00000008945 ProSitePatterns PS00348 IPR002117 219 231 - p53 tumour suppressor family
ENSMPUP00000008945 SUPERFAMILY SSF47719 IPR010991 301 340 0.00e-00 p53, tetramerisation domain
ENSMPUP00000008945 SUPERFAMILY SSF49417 IPR008967 78 269 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSMPUP00000008945 PF00870 0 P53 P53 DNA-binding domain
ENSMPUP00000008945 PF07710 7e-17 P53_tetramer P53 tetramerisation motif
ENSMPUP00000008945 PF08563 8.6e-12 P53_TAD P53 transactivation motif

Gene Ontology Annotation
Protein Entry Name Space Description
ENSMPUP00000008945 GO:0000733 biological_process DNA strand renaturation
ENSMPUP00000008945 GO:0006289 biological_process nucleotide-excision repair
ENSMPUP00000008945 GO:0006351 biological_process transcription, DNA-templated
ENSMPUP00000008945 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSMPUP00000008945 GO:0006915 biological_process apoptotic process
ENSMPUP00000008945 GO:0007049 biological_process cell cycle
ENSMPUP00000008945 GO:0007275 biological_process multicellular organismal development
ENSMPUP00000008945 GO:0007569 biological_process cell aging
ENSMPUP00000008945 GO:0012501 biological_process programmed cell death
ENSMPUP00000008945 GO:0030308 biological_process negative regulation of cell growth
ENSMPUP00000008945 GO:0051262 biological_process protein tetramerization
ENSMPUP00000008945 GO:0090200 biological_process positive regulation of release of cytochrome c from mitochondria
ENSMPUP00000008945 GO:0097252 biological_process oligodendrocyte apoptotic process
ENSMPUP00000008945 GO:0005634 cellular_component nucleus
ENSMPUP00000008945 GO:0005730 cellular_component nucleolus
ENSMPUP00000008945 GO:0005737 cellular_component cytoplasm
ENSMPUP00000008945 GO:0005739 cellular_component mitochondrion
ENSMPUP00000008945 GO:0005759 cellular_component mitochondrial matrix
ENSMPUP00000008945 GO:0005783 cellular_component endoplasmic reticulum
ENSMPUP00000008945 GO:0003677 molecular_function DNA binding
ENSMPUP00000008945 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSMPUP00000008945 GO:0005507 molecular_function copper ion binding
ENSMPUP00000008945 GO:0005524 molecular_function ATP binding
ENSMPUP00000008945 GO:0044212 molecular_function transcription regulatory region DNA binding
ENSMPUP00000008945 GO:0046872 molecular_function metal ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
10029 Cricetulus griseus 100682525 9305 Sarcophilus harrisii 100922473
9597 Pan paniscus 100973941 39432 Saimiri boliviensis 101043647
43179 Ictidomys tridecemlineatus 101957738 8083 Xiphophorus maculatus 102219062
13735 Pelodiscus sinensis 102448135 10116 Rattus norvegicus 24842
9606 Homo sapiens 7157 9615 Canis familiaris ENSCAFG00000016714
9361 Dasypus novemcinctus ENSDNOG00000005252 9796 Equus caballus ENSECAG00000008126
9371 Echinops telfairi ENSETEG00000008987 7897 Latimeria chalumnae ENSLACG00000014014
9785 Loxodonta africana ENSLAFG00000007483 9315 Macropus eugenii ENSMEUG00000013135
30608 Microcebus murinus ENSMICG00000014853 59463 Myotis lucifugus ENSMLUG00000006411
10141 Cavia porcellus 100379269 9483 Callithrix jacchus 100415710
9601 Pongo abelii 100435218 9555 Papio anubis 101006608
9595 Gorilla gorilla 101133524 9598 Pan troglodytes 455214
9685 Felis catus 493847 9365 Erinaceus europaeus ENSEEUG00000014573
132908 Pteropus vampyrus ENSPVAG00000016317 8364 Xenopus tropicalis ENSXETG00000025055
61853 Nomascus leucogenys ENSNLEG00000009730 9986 Oryctolagus cuniculus ENSOCUG00000001138
30611 Otolemur garnettii ENSOGAG00000016871 9978 Ochotona princeps ENSOPRG00000006441
9813 Procavia capensis ENSPCAG00000012725 42254 Sorex araneus ENSSARG00000006206
37347 Tupaia belangeri ENSTBEG00000011771 9739 Tursiops truncatus ENSTTRG00000010250