Basic Information
Gene ID 455214
Gene Name TP53
Full Name Cellular tumor antigen p53
Organism Pan troglodytes [9598]

Cross Reference
UniProt H2QC53 UniGene NULL
PDB NULL OMIM NULL
KEGG ptr:455214 UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSPTRP00000014836 Gene3D G3DSA:2.60.40.720 IPR012346 94 297 3.20e-97 p53/RUNT-type transcription factor, DNA-binding domain
ENSPTRP00000014836 Gene3D G3DSA:4.10.170.10 IPR010991 319 359 1.70e-21 p53, tetramerisation domain
ENSPTRP00000014836 PANTHER PTHR11447 IPR002117 1 393 0.00e-00 p53 tumour suppressor family
ENSPTRP00000014836 Pfam PF00870 IPR011615 95 288 1.20e-109 p53, DNA-binding domain
ENSPTRP00000014836 Pfam PF07710 IPR010991 318 358 1.00e-19 p53, tetramerisation domain
ENSPTRP00000014836 Pfam PF08563 IPR013872 6 29 2.20e-10 p53 transactivation domain
ENSPTRP00000014836 PRINTS PR00386 IPR002117 116 142 6.00e-87 p53 tumour suppressor family
ENSPTRP00000014836 PRINTS PR00386 IPR002117 158 179 6.00e-87 p53 tumour suppressor family
ENSPTRP00000014836 PRINTS PR00386 IPR002117 213 234 6.00e-87 p53 tumour suppressor family
ENSPTRP00000014836 PRINTS PR00386 IPR002117 236 258 6.00e-87 p53 tumour suppressor family
ENSPTRP00000014836 PRINTS PR00386 IPR002117 264 286 6.00e-87 p53 tumour suppressor family
ENSPTRP00000014836 PRINTS PR00386 IPR002117 326 350 6.00e-87 p53 tumour suppressor family
ENSPTRP00000014836 ProSitePatterns PS00348 IPR002117 237 249 - p53 tumour suppressor family
ENSPTRP00000014836 SUPERFAMILY SSF47719 IPR010991 319 357 0.00e-00 p53, tetramerisation domain
ENSPTRP00000014836 SUPERFAMILY SSF49417 IPR008967 97 287 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSPTRP00000014836 PF00870 0 P53 P53 DNA-binding domain
ENSPTRP00000014836 PF07710 5.5e-20 P53_tetramer P53 tetramerisation motif
ENSPTRP00000014836 PF08563 1e-10 P53_TAD P53 transactivation motif

Gene Ontology Annotation
Protein Entry Name Space Description
ENSPTRP00000014836 GO:0000733 biological_process DNA strand renaturation
ENSPTRP00000014836 GO:0006289 biological_process nucleotide-excision repair
ENSPTRP00000014836 GO:0006351 biological_process transcription, DNA-templated
ENSPTRP00000014836 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSPTRP00000014836 GO:0006915 biological_process apoptotic process
ENSPTRP00000014836 GO:0007049 biological_process cell cycle
ENSPTRP00000014836 GO:0007275 biological_process multicellular organismal development
ENSPTRP00000014836 GO:0007569 biological_process cell aging
ENSPTRP00000014836 GO:0012501 biological_process programmed cell death
ENSPTRP00000014836 GO:0030308 biological_process negative regulation of cell growth
ENSPTRP00000014836 GO:0051262 biological_process protein tetramerization
ENSPTRP00000014836 GO:0090200 biological_process positive regulation of release of cytochrome c from mitochondria
ENSPTRP00000014836 GO:0097252 biological_process oligodendrocyte apoptotic process
ENSPTRP00000014836 GO:0005634 cellular_component nucleus
ENSPTRP00000014836 GO:0005730 cellular_component nucleolus
ENSPTRP00000014836 GO:0005737 cellular_component cytoplasm
ENSPTRP00000014836 GO:0005739 cellular_component mitochondrion
ENSPTRP00000014836 GO:0005759 cellular_component mitochondrial matrix
ENSPTRP00000014836 GO:0005783 cellular_component endoplasmic reticulum
ENSPTRP00000014836 GO:0003677 molecular_function DNA binding
ENSPTRP00000014836 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSPTRP00000014836 GO:0005507 molecular_function copper ion binding
ENSPTRP00000014836 GO:0005524 molecular_function ATP binding
ENSPTRP00000014836 GO:0044212 molecular_function transcription regulatory region DNA binding
ENSPTRP00000014836 GO:0046872 molecular_function metal ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
10141 Cavia porcellus 100379269 9483 Callithrix jacchus 100415710
10029 Cricetulus griseus 100682525 8128 Oreochromis niloticus 100702587
34638 Metaseiulus occidentalis 100907785 9305 Sarcophilus harrisii 100922473
9597 Pan paniscus 100973941 9555 Papio anubis 101006608
39432 Saimiri boliviensis 101043647 43179 Ictidomys tridecemlineatus 101957738
8083 Xiphophorus maculatus 102219062 13735 Pelodiscus sinensis 102448135
10116 Rattus norvegicus 24842 9601 Pongo abelii 100435218
9595 Gorilla gorilla 101133524 9685 Felis catus 493847
9606 Homo sapiens 7157 9615 Canis familiaris ENSCAFG00000016714
9361 Dasypus novemcinctus ENSDNOG00000005252 9796 Equus caballus ENSECAG00000008126
9365 Erinaceus europaeus ENSEEUG00000014573 9371 Echinops telfairi ENSETEG00000008987
7897 Latimeria chalumnae ENSLACG00000014014 9785 Loxodonta africana ENSLAFG00000007483
9315 Macropus eugenii ENSMEUG00000013135 30608 Microcebus murinus ENSMICG00000014853
59463 Myotis lucifugus ENSMLUG00000006411 9669 Mustela putorius furo ENSMPUG00000009017
61853 Nomascus leucogenys ENSNLEG00000009730 9986 Oryctolagus cuniculus ENSOCUG00000001138
30611 Otolemur garnettii ENSOGAG00000016871 9978 Ochotona princeps ENSOPRG00000006441
9813 Procavia capensis ENSPCAG00000012725 132908 Pteropus vampyrus ENSPVAG00000016317
42254 Sorex araneus ENSSARG00000006206 37347 Tupaia belangeri ENSTBEG00000011771
9739 Tursiops truncatus ENSTTRG00000010250 8364 Xenopus tropicalis ENSXETG00000025055