Basic Information
Gene ID ENSOGAG00000016871
Gene Name TP53
Full Name Cellular tumor antigen p53
Organism Otolemur garnettii [30611]

Cross Reference
UniProt H0XGB0 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSOGAP00000015106 Gene3D G3DSA:2.60.40.720 IPR012346 92 295 1.50e-93 p53/RUNT-type transcription factor, DNA-binding domain
ENSOGAP00000015106 Gene3D G3DSA:4.10.170.10 IPR010991 319 359 4.10e-18 p53, tetramerisation domain
ENSOGAP00000015106 PANTHER PTHR11447 IPR002117 1 393 0.00e-00 p53 tumour suppressor family
ENSOGAP00000015106 Pfam PF00870 IPR011615 93 288 3.90e-106 p53, DNA-binding domain
ENSOGAP00000015106 Pfam PF07710 IPR010991 318 358 4.80e-18 p53, tetramerisation domain
ENSOGAP00000015106 Pfam PF08563 IPR013872 5 29 3.40e-12 p53 transactivation domain
ENSOGAP00000015106 PRINTS PR00386 IPR002117 113 139 1.80e-71 p53 tumour suppressor family
ENSOGAP00000015106 PRINTS PR00386 IPR002117 155 176 1.80e-71 p53 tumour suppressor family
ENSOGAP00000015106 PRINTS PR00386 IPR002117 210 231 1.80e-71 p53 tumour suppressor family
ENSOGAP00000015106 PRINTS PR00386 IPR002117 233 255 1.80e-71 p53 tumour suppressor family
ENSOGAP00000015106 PRINTS PR00386 IPR002117 326 350 1.80e-71 p53 tumour suppressor family
ENSOGAP00000015106 ProSitePatterns PS00348 IPR002117 234 246 - p53 tumour suppressor family
ENSOGAP00000015106 SUPERFAMILY SSF47719 IPR010991 320 358 0.00e-00 p53, tetramerisation domain
ENSOGAP00000015106 SUPERFAMILY SSF49417 IPR008967 94 287 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSOGAP00000015106 PF00870 0 P53 P53 DNA-binding domain
ENSOGAP00000015106 PF07710 2.6e-18 P53_tetramer P53 tetramerisation motif
ENSOGAP00000015106 PF08563 1.2e-12 P53_TAD P53 transactivation motif

Gene Ontology Annotation
Protein Entry Name Space Description
ENSOGAP00000015106 GO:0000733 biological_process DNA strand renaturation
ENSOGAP00000015106 GO:0006289 biological_process nucleotide-excision repair
ENSOGAP00000015106 GO:0006351 biological_process transcription, DNA-templated
ENSOGAP00000015106 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSOGAP00000015106 GO:0006915 biological_process apoptotic process
ENSOGAP00000015106 GO:0007049 biological_process cell cycle
ENSOGAP00000015106 GO:0007275 biological_process multicellular organismal development
ENSOGAP00000015106 GO:0007569 biological_process cell aging
ENSOGAP00000015106 GO:0012501 biological_process programmed cell death
ENSOGAP00000015106 GO:0030308 biological_process negative regulation of cell growth
ENSOGAP00000015106 GO:0051262 biological_process protein tetramerization
ENSOGAP00000015106 GO:0090200 biological_process positive regulation of release of cytochrome c from mitochondria
ENSOGAP00000015106 GO:0097252 biological_process oligodendrocyte apoptotic process
ENSOGAP00000015106 GO:0005634 cellular_component nucleus
ENSOGAP00000015106 GO:0005730 cellular_component nucleolus
ENSOGAP00000015106 GO:0005737 cellular_component cytoplasm
ENSOGAP00000015106 GO:0005739 cellular_component mitochondrion
ENSOGAP00000015106 GO:0005759 cellular_component mitochondrial matrix
ENSOGAP00000015106 GO:0005783 cellular_component endoplasmic reticulum
ENSOGAP00000015106 GO:0003677 molecular_function DNA binding
ENSOGAP00000015106 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSOGAP00000015106 GO:0005507 molecular_function copper ion binding
ENSOGAP00000015106 GO:0005524 molecular_function ATP binding
ENSOGAP00000015106 GO:0044212 molecular_function transcription regulatory region DNA binding
ENSOGAP00000015106 GO:0046872 molecular_function metal ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9597 Pan paniscus 100973941 8083 Xiphophorus maculatus 102219062
9615 Canis familiaris ENSCAFG00000016714 69293 Gasterosteus aculeatus ENSGACG00000019378
61853 Nomascus leucogenys ENSNLEG00000009730 9986 Oryctolagus cuniculus ENSOCUG00000001138
10141 Cavia porcellus 100379269 9483 Callithrix jacchus 100415710
9601 Pongo abelii 100435218 10029 Cricetulus griseus 100682525
8128 Oreochromis niloticus 100702587 9305 Sarcophilus harrisii 100922473
9555 Papio anubis 101006608 39432 Saimiri boliviensis 101043647
9595 Gorilla gorilla 101133524 43179 Ictidomys tridecemlineatus 101957738
13735 Pelodiscus sinensis 102448135 10116 Rattus norvegicus 24842
9598 Pan troglodytes 455214 9685 Felis catus 493847
9606 Homo sapiens 7157 9361 Dasypus novemcinctus ENSDNOG00000005252
9796 Equus caballus ENSECAG00000008126 9365 Erinaceus europaeus ENSEEUG00000014573
9371 Echinops telfairi ENSETEG00000008987 7897 Latimeria chalumnae ENSLACG00000014014
9785 Loxodonta africana ENSLAFG00000007483 9315 Macropus eugenii ENSMEUG00000013135
30608 Microcebus murinus ENSMICG00000014853 59463 Myotis lucifugus ENSMLUG00000006411
9669 Mustela putorius furo ENSMPUG00000009017 9978 Ochotona princeps ENSOPRG00000006441
9813 Procavia capensis ENSPCAG00000012725 132908 Pteropus vampyrus ENSPVAG00000016317
42254 Sorex araneus ENSSARG00000006206 37347 Tupaia belangeri ENSTBEG00000011771
9739 Tursiops truncatus ENSTTRG00000010250 8364 Xenopus tropicalis ENSXETG00000025055