Basic Information
Gene ID 100435218
Gene Name TP53
Full Name Cellular tumor antigen p53
Organism Pongo abelii [9601]

Cross Reference
UniProt H2NSL2 UniGene NULL
PDB NULL OMIM NULL
KEGG pon:100435218 UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSPPYP00000008923 Gene3D G3DSA:2.60.40.720 IPR012346 94 297 2.60e-97 p53/RUNT-type transcription factor, DNA-binding domain
ENSPPYP00000008923 Gene3D G3DSA:4.10.170.10 IPR010991 319 359 1.70e-21 p53, tetramerisation domain
ENSPPYP00000008923 PANTHER PTHR11447 IPR002117 1 393 0.00e-00 p53 tumour suppressor family
ENSPPYP00000008923 Pfam PF00870 IPR011615 95 288 1.10e-109 p53, DNA-binding domain
ENSPPYP00000008923 Pfam PF07710 IPR010991 318 358 1.00e-19 p53, tetramerisation domain
ENSPPYP00000008923 Pfam PF08563 IPR013872 6 29 2.20e-10 p53 transactivation domain
ENSPPYP00000008923 PRINTS PR00386 IPR002117 116 142 6.00e-87 p53 tumour suppressor family
ENSPPYP00000008923 PRINTS PR00386 IPR002117 158 179 6.00e-87 p53 tumour suppressor family
ENSPPYP00000008923 PRINTS PR00386 IPR002117 213 234 6.00e-87 p53 tumour suppressor family
ENSPPYP00000008923 PRINTS PR00386 IPR002117 236 258 6.00e-87 p53 tumour suppressor family
ENSPPYP00000008923 PRINTS PR00386 IPR002117 264 286 6.00e-87 p53 tumour suppressor family
ENSPPYP00000008923 PRINTS PR00386 IPR002117 326 350 6.00e-87 p53 tumour suppressor family
ENSPPYP00000008923 ProSitePatterns PS00348 IPR002117 237 249 - p53 tumour suppressor family
ENSPPYP00000008923 SUPERFAMILY SSF47719 IPR010991 319 357 0.00e-00 p53, tetramerisation domain
ENSPPYP00000008923 SUPERFAMILY SSF49417 IPR008967 97 287 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSPPYP00000008923 PF00870 0 P53 P53 DNA-binding domain
ENSPPYP00000008923 PF07710 5.3e-20 P53_tetramer P53 tetramerisation motif
ENSPPYP00000008923 PF08563 1e-10 P53_TAD P53 transactivation motif

Gene Ontology Annotation
Protein Entry Name Space Description
ENSPPYP00000008923 GO:0000733 biological_process DNA strand renaturation
ENSPPYP00000008923 GO:0006289 biological_process nucleotide-excision repair
ENSPPYP00000008923 GO:0006351 biological_process transcription, DNA-templated
ENSPPYP00000008923 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSPPYP00000008923 GO:0006915 biological_process apoptotic process
ENSPPYP00000008923 GO:0007049 biological_process cell cycle
ENSPPYP00000008923 GO:0007275 biological_process multicellular organismal development
ENSPPYP00000008923 GO:0007569 biological_process cell aging
ENSPPYP00000008923 GO:0012501 biological_process programmed cell death
ENSPPYP00000008923 GO:0030308 biological_process negative regulation of cell growth
ENSPPYP00000008923 GO:0051262 biological_process protein tetramerization
ENSPPYP00000008923 GO:0090200 biological_process positive regulation of release of cytochrome c from mitochondria
ENSPPYP00000008923 GO:0097252 biological_process oligodendrocyte apoptotic process
ENSPPYP00000008923 GO:0005634 cellular_component nucleus
ENSPPYP00000008923 GO:0005730 cellular_component nucleolus
ENSPPYP00000008923 GO:0005737 cellular_component cytoplasm
ENSPPYP00000008923 GO:0005739 cellular_component mitochondrion
ENSPPYP00000008923 GO:0005759 cellular_component mitochondrial matrix
ENSPPYP00000008923 GO:0005783 cellular_component endoplasmic reticulum
ENSPPYP00000008923 GO:0003677 molecular_function DNA binding
ENSPPYP00000008923 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSPPYP00000008923 GO:0005507 molecular_function copper ion binding
ENSPPYP00000008923 GO:0005524 molecular_function ATP binding
ENSPPYP00000008923 GO:0044212 molecular_function transcription regulatory region DNA binding
ENSPPYP00000008923 GO:0046872 molecular_function metal ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7425 Nasonia vitripennis 100116126 7029 Acyrthosiphon pisum 100160742
10224 Saccoglossus kowalevskii 100313697 10141 Cavia porcellus 100379269
9483 Callithrix jacchus 100415710 7460 Apis mellifera 100577122
30195 Bombus terrestris 100648488 10029 Cricetulus griseus 100682525
8128 Oreochromis niloticus 100702587 132113 Bombus impatiens 100748472
7463 Apis florea 100862994 143995 Megachile rotundata 100880552
34638 Metaseiulus occidentalis 100907785 9305 Sarcophilus harrisii 100922473
9597 Pan paniscus 100973941 9555 Papio anubis 101006608
39432 Saimiri boliviensis 101043647 9595 Gorilla gorilla 101133524
6087 Hydra magnipapillata 101235318 43179 Ictidomys tridecemlineatus 101957738
8083 Xiphophorus maculatus 102219062 13735 Pelodiscus sinensis 102448135
10116 Rattus norvegicus 24842 9598 Pan troglodytes 455214
9685 Felis catus 493847 7070 Tribolium castaneum 655327
9606 Homo sapiens 7157 7668 Strongylocentrotus purpuratus 756859
9615 Canis familiaris ENSCAFG00000016714 7719 Ciona intestinalis ENSCING00000002175
51511 Ciona savignyi ENSCSAVG00000009964 9361 Dasypus novemcinctus ENSDNOG00000005252
9796 Equus caballus ENSECAG00000008126 9365 Erinaceus europaeus ENSEEUG00000014573
9371 Echinops telfairi ENSETEG00000008987 69293 Gasterosteus aculeatus ENSGACG00000013629
8049 Gadus morhua ENSGMOG00000000413 7897 Latimeria chalumnae ENSLACG00000014014
9785 Loxodonta africana ENSLAFG00000007483 9315 Macropus eugenii ENSMEUG00000013135
30608 Microcebus murinus ENSMICG00000014853 59463 Myotis lucifugus ENSMLUG00000006411
9669 Mustela putorius furo ENSMPUG00000009017 61853 Nomascus leucogenys ENSNLEG00000009730
9986 Oryctolagus cuniculus ENSOCUG00000001138 30611 Otolemur garnettii ENSOGAG00000016871
9978 Ochotona princeps ENSOPRG00000006441 9813 Procavia capensis ENSPCAG00000012725
7757 Petromyzon marinus ENSPMAG00000009535 132908 Pteropus vampyrus ENSPVAG00000016317
42254 Sorex araneus ENSSARG00000006206 37347 Tupaia belangeri ENSTBEG00000011771
99883 Tetraodon nigroviridis ENSTNIG00000010137 31033 Takifugu rubripes ENSTRUG00000012107
9739 Tursiops truncatus ENSTTRG00000010250 8364 Xenopus tropicalis ENSXETG00000025055