Basic Information
Gene ID ENSXETG00000025055
Gene Name tp53
Full Name Cellular tumor antigen p53
Organism Xenopus tropicalis [8364]

Cross Reference
UniProt F7A9M9 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSXETP00000053759 Gene3D G3DSA:2.60.40.720 IPR012346 68 268 7.80e-90 p53/RUNT-type transcription factor, DNA-binding domain
ENSXETP00000053759 Gene3D G3DSA:4.10.170.10 IPR010991 305 337 3.80e-13 p53, tetramerisation domain
ENSXETP00000053759 PANTHER PTHR11447 IPR002117 1 366 0.00e-00 p53 tumour suppressor family
ENSXETP00000053759 Pfam PF00870 IPR011615 69 263 5.10e-108 p53, DNA-binding domain
ENSXETP00000053759 Pfam PF07710 IPR010991 290 336 6.20e-14 p53, tetramerisation domain
ENSXETP00000053759 Pfam PF08563 IPR013872 4 28 1.90e-11 p53 transactivation domain
ENSXETP00000053759 PRINTS PR00386 IPR002117 132 153 1.20e-80 p53 tumour suppressor family
ENSXETP00000053759 PRINTS PR00386 IPR002117 188 209 1.20e-80 p53 tumour suppressor family
ENSXETP00000053759 PRINTS PR00386 IPR002117 211 233 1.20e-80 p53 tumour suppressor family
ENSXETP00000053759 PRINTS PR00386 IPR002117 239 261 1.20e-80 p53 tumour suppressor family
ENSXETP00000053759 PRINTS PR00386 IPR002117 304 328 1.20e-80 p53 tumour suppressor family
ENSXETP00000053759 PRINTS PR00386 IPR002117 90 116 1.20e-80 p53 tumour suppressor family
ENSXETP00000053759 ProSitePatterns PS00348 IPR002117 212 224 - p53 tumour suppressor family
ENSXETP00000053759 SUPERFAMILY SSF47719 IPR010991 304 336 0.00e-00 p53, tetramerisation domain
ENSXETP00000053759 SUPERFAMILY SSF49417 IPR008967 71 261 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSXETP00000053759 PF00870 0 P53 P53 DNA-binding domain
ENSXETP00000053759 PF07710 3.2e-14 P53_tetramer P53 tetramerisation motif
ENSXETP00000053759 PF08563 9.4e-12 P53_TAD P53 transactivation motif

Gene Ontology Annotation
Protein Entry Name Space Description
ENSXETP00000053759 GO:0006351 biological_process transcription, DNA-templated
ENSXETP00000053759 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSXETP00000053759 GO:0006915 biological_process apoptotic process
ENSXETP00000053759 GO:0007049 biological_process cell cycle
ENSXETP00000053759 GO:0051262 biological_process protein tetramerization
ENSXETP00000053759 GO:0005634 cellular_component nucleus
ENSXETP00000053759 GO:0005737 cellular_component cytoplasm
ENSXETP00000053759 GO:0005739 cellular_component mitochondrion
ENSXETP00000053759 GO:0003677 molecular_function DNA binding
ENSXETP00000053759 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSXETP00000053759 GO:0044212 molecular_function transcription regulatory region DNA binding
ENSXETP00000053759 GO:0046872 molecular_function metal ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7425 Nasonia vitripennis 100116126 10141 Cavia porcellus 100379269
9483 Callithrix jacchus 100415710 10029 Cricetulus griseus 100682525
8128 Oreochromis niloticus 100702587 9305 Sarcophilus harrisii 100922473
9597 Pan paniscus 100973941 39432 Saimiri boliviensis 101043647
43179 Ictidomys tridecemlineatus 101957738 8083 Xiphophorus maculatus 102219062
13735 Pelodiscus sinensis 102448135 10116 Rattus norvegicus 24842
9606 Homo sapiens 7157 9615 Canis familiaris ENSCAFG00000016714
9361 Dasypus novemcinctus ENSDNOG00000005252 9371 Echinops telfairi ENSETEG00000008987
69293 Gasterosteus aculeatus ENSGACG00000019378 7897 Latimeria chalumnae ENSLACG00000014014
9785 Loxodonta africana ENSLAFG00000007483 9315 Macropus eugenii ENSMEUG00000013135
30608 Microcebus murinus ENSMICG00000014853 59463 Myotis lucifugus ENSMLUG00000006411
9669 Mustela putorius furo ENSMPUG00000009017 61853 Nomascus leucogenys ENSNLEG00000009730
9986 Oryctolagus cuniculus ENSOCUG00000001138 30611 Otolemur garnettii ENSOGAG00000016871
9978 Ochotona princeps ENSOPRG00000006441 8090 Oryzias latipes ENSORLG00000006390
9813 Procavia capensis ENSPCAG00000012725 42254 Sorex araneus ENSSARG00000006206
99883 Tetraodon nigroviridis ENSTNIG00000010137 31033 Takifugu rubripes ENSTRUG00000012107
9739 Tursiops truncatus ENSTTRG00000010250 9601 Pongo abelii 100435218
9555 Papio anubis 101006608 9595 Gorilla gorilla 101133524
9598 Pan troglodytes 455214 9685 Felis catus 493847
9365 Erinaceus europaeus ENSEEUG00000014573